Effective targets of intervention on generalized anxiety symptoms across whole adolescence and emerging adulthood: network analysis and insilico intervention.

Early-onset generalized anxiety symptoms have severe impacts on youth development. Age differences in anxiety symptoms are obscure. Effective intervention targets need further investigation. Adolescents and emerging adults (N = 65,048; 10–24 years; 50.63% female; Mage = 15.78, SD = 3.62) reported ge...

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Publicado en:European Child & Adolescent Psychiatry Vol. 34; no. 7; pp. 2133 - 2145
Autores principales: Li, Feng, Zhang, Yihong, Fang, Yuan, Chen, Zhiyan
Formato: research tables/charts Journal Article
Publicado: Springer Nature Jul2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2025
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00787-024-02626-0
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        atl: Effective targets of intervention on generalized anxiety symptoms across whole adolescence and emerging adulthood: network analysis and insilico intervention.
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        au:
          Li, Feng
          Zhang, Yihong
          Fang, Yuan
          Chen, Zhiyan
        affil: https://ror.org/034t30j35 CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, 16 Lincui Road, Chaoyang District, 100101, Beijing, China
      sug:
        subj:
          Generalized Anxiety Disorder Symptoms
          Generalized Anxiety Disorder Therapy
          Computer Simulation
          Age Factors
          Cognitive Therapy
          Treatment Outcomes
          Human
          Funding Source
          China
          Male
          Female
          Child
          Adolescence
          Young Adult
          Generalized Anxiety Disorder Prevention and Control
          Adolescent Behavior
          Adolescent Development
          Worry
          Child: 6-12 years
          Adolescent: 13-18 years
          Male
          Female
      ab: Early-onset generalized anxiety symptoms have severe impacts on youth development. Age differences in anxiety symptoms are obscure. Effective intervention targets need further investigation. Adolescents and emerging adults (N = 65,048; 10–24 years; 50.63% female; Mage = 15.78, SD = 3.62) reported generalized anxiety symptoms and demographic information. They were divided into four subgroups: early adolescence (10–12 years), middle adolescence (13–15 years), late adolescence (16–18 years), and emerging adulthood (19–24 years) according to their developmental stages. Network analysis was used to compare age differences in symptom roles between subgroups. In silico intervention (i.e., computer simulation-based intervention) was employed to disclose the intervention targets (i.e., treatment and prevention targets) and efficacy of symptom-specific interventions within dynamic network systems. Network comparison tests indicated that the involvement of anxiety symptoms in networks varied with developmental stages, particularly between early and middle adolescence. In silico intervention revealed that nervousness was the most effective treatment target to alleviate network state in all subgroups. Excessive worry in early adolescence and uncontrollable worry from middle adolescence to emerging adulthood emerged as the most effective prevention targets. The current study highlights the importance of middle adolescence as a crucial phase for preventive intervention and emphasizes the need for differentiated prevention and treatment strategies for particular populations.
      pubtype: Academic Journal
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        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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