Emotion regulation strategy and its relationship with emotional dysregulation in children with attention-deficit/hyperactivity disorder: behavioral and brain findings.

Important associations between emotional dysregulation (ED) and ADHD have been identified in adults, with a key manifestation of this being differential use of emotion regulation strategies: reduced use of cognitive reappraisal (CR), but elevated expressive suppression (ES). These associations have...

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Published in:European Child & Adolescent Psychiatry Vol. 34; no. 7; pp. 2241 - 2253
Main Authors: Liu, Qianrong, Feng, Yuan, Chen, Wai, Zhu, Yu, Preece, David A., Gao, Yuan, Luo, Xiangsheng, Dang, Chen, Wang, Yufeng, Sun, Li, Liu, Lu
Format: diagnostic images research tables/charts Journal Article
Published: Springer Nature Jul2025
Online Access:View this record in EBSCOhost
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        atl: Emotion regulation strategy and its relationship with emotional dysregulation in children with attention-deficit/hyperactivity disorder: behavioral and brain findings.
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        au:
          Liu, Qianrong
          Feng, Yuan
          Chen, Wai
          Zhu, Yu
          Preece, David A.
          Gao, Yuan
          Luo, Xiangsheng
          Dang, Chen
          Wang, Yufeng
          Sun, Li
          Liu, Lu
        affil: https://ror.org/05rzcwg85 NHC Key Laboratory of Mental Health (Peking University), Peking University Sixth Hospital, Institute of Mental Health, 100191, Beijing, China
      sug:
        subj:
          Emotional Regulation Evaluation
          Affective Disorders In Infancy and Childhood
          Attention Deficit Hyperactivity Disorder In Infancy and Childhood
          Brain Physiopathology
          Cognition Evaluation
          Child Behavior
          Human
          Female
          Male
          Child
          Scales
          Questionnaires
          Control Group
          Magnetic Resonance Imaging Methods
          Functional Connectivity
          Amygdala
          Neuroradiography
          Comparative Studies
          Correlation Coefficient
          Mediation Analysis
          Regression
          Data Analysis Software
          Confidence Intervals
          Descriptive Statistics
          Child: 6-12 years
          Female
          Male
      ab: Important associations between emotional dysregulation (ED) and ADHD have been identified in adults, with a key manifestation of this being differential use of emotion regulation strategies: reduced use of cognitive reappraisal (CR), but elevated expressive suppression (ES). These associations have been observed at both behavioral and neuroimaging levels. The present study aims to explore the use of CR and ES in children with ADHD, and their relationship to ED. 148 children with ADHD and 265 healthy controls (age 9–16 years) were recruited and evaluated and correlated their ED, CR, and ES. Resting-state fMRI functional connectivity, with 6 amygdala subregions as regions-of-interest, were analyzed in a subsample to identify potential neural correlates. Children with ADHD showed significant higher ED, and lower use of both CR and ES. A significant negative correlation was found between CR and ED. Mediation analysis indicated that CR has an indirect influence on the relationship between ADHD diagnosis and ED. In the neuroimaging analyses, the functional connectivity between the right superficial amygdala and left middle occipital gyrus showed a significant group-by-ES interaction, highlighting potential neural correlates for elevated ED in children with ADHD. Children with ADHD expressed elevated levels of ED, and used less CR and ES compared to healthy controls. The lower use of ES may relate to abnormal amygdala connectivity in children with ADHD. This finding suggested that brain immaturity in children may preclude effective deployment of ES in emotion regulation processes.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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