Diagnostic Performance of the Milan System for Reporting Salivary Gland Cytopathology and a Proposed Algorithm for Fine-Needle Aspiration Cytology of Salivary Gland Lesions.
Introduction: We evaluated concordance between Milan System for Reporting Salivary Gland Cytopathology (MSRSGC)-based categorization of salivary gland masses/lesions screened by fine-needle aspiration cytology (FNAC) and final histopathologic diagnoses, aiming to identify factors predictive of conco...
| Published in: | Acta Cytologica Vol. 69; no. 4; pp. 324 - 336 |
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| Main Authors: | , , , , , , , , , , , , |
| Format: | diagnostic images pictorial research tables/charts Journal Article |
| Published: |
Karger AG
2025
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187240157&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187240157 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00015547 10OE jtl: Acta Cytologica issn: 00015547 maglogo: N pubinfo: dt: 2025 vid: 69 iid: 4 pid: 2485 pub: Karger AG artinfo: ui: 187240157 185857684 187240157 187240157 10.1159/000546005 187240157 ppf: 324 ppct: 12 formats: tig: atl: Diagnostic Performance of the Milan System for Reporting Salivary Gland Cytopathology and a Proposed Algorithm for Fine-Needle Aspiration Cytology of Salivary Gland Lesions. aug: au: Mochizuki, Norihide Fujita, Hirotaka Tajiri, Takuma Ueda, Masataka Kurata, Makiko Inomoto, Chie Sugiyama, Tomoko Maki, Daisuke Shiraishi, Shuichi Machida, Tomohisa Ito, Hitoshi Masugi, Yohei Nakamura, Naoya affil: Department of Laboratory Medicine, Tokai University Hospital, Kanagawa, Japan sug: subj: Salivary Gland Neoplasms Classification Salivary Gland Neoplasms Diagnosis Salivary Glands Pathology Cytodiagnosis Biopsy, Needle Cytology Algorithms Case Management Histological Techniques Human Child Adolescence Adult Middle Age Aged Aged, 80 and Over Male Female Funding Source Retrospective Design Record Review Salivary Gland Neoplasms Pathology Descriptive Statistics Body Surface Area Otolaryngologists Child: 6-12 years Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Introduction: We evaluated concordance between Milan System for Reporting Salivary Gland Cytopathology (MSRSGC)-based categorization of salivary gland masses/lesions screened by fine-needle aspiration cytology (FNAC) and final histopathologic diagnoses, aiming to identify factors predictive of concordance, with the goal of appropriate case management. Methods: The study was retrospective and involved 101 cases of salivary mass/lesion examined by FNAC. We compared MSRSGC categories against the final histopathologic classes (non-neoplasm, benign neoplasm, or malignant neoplasm) and calculated diagnostic concordance in each class. Concordance was defined as: MSRSGC categorization of a lesion as a category II lesion and a histopathologic classification as a non-neoplasm; MSRSGC categorization of a lesion as a category IV-A lesion and a histopathologic classification as a benign neoplasm; or MSRSGC categorization of a lesion as a category V or VI lesion and a histopathologic classification as a malignant neoplasm. We then compared clinicopathologic factors between concordant and discordant cases. Results: Diagnostic concordance for non-neoplasms, benign neoplasms, malignant neoplasms, and total cases was 81.8% (9/11), 81.7% (58/71), 66.6% (8/12), and 79.8% (75/94), respectively, with no significant between-class difference. We found the shortest distance from the body surface to the salivary lesion differed significantly between the concordant group and the discordant group (5.35 mm vs. 7.30 mm), and the optimal cutoff was determined to be 8.00 mm (p < 0.01). Conclusion: Based on the distance of either <8 mm or ≥8 mm from the body surface to the mass/lesion, we believe our proposed FNAC algorithm of treatment strategies is a reliable guide for otolaryngologists on evaluating salivary gland lesions. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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