Pulmonary CT Registration Network Based on Deformable Cross Attention.

Current Transformer structure utilizes the self-attention mechanism to model global contextual relevance within image, which makes an impact on medical image registration. However, the use of Transformer in handling large deformation lung CT registration is relatively straightforwardly. These models...

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Bibliographic Details
Published in:Journal of Imaging Informatics in Medicine Vol. 38; no. 4; pp. 1963 - 1976
Main Authors: Ren, Meirong, Xue, Peng, Ji, Huizhong, Zhang, Zhili, Dong, Enqing
Format: diagnostic images equations & formulas research tables/charts Journal Article
Published: Springer Nature Aug2025
Online Access:View this record in EBSCOhost
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      dt: Aug2025
      vid: 38
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      pub: Springer Nature
      place: New York, New York
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        187278963
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        10.1007/s10278-024-01324-2
        187278963
      ppf: 1963
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      tig:
        atl: Pulmonary CT Registration Network Based on Deformable Cross Attention.
      aug:
        au:
          Ren, Meirong
          Xue, Peng
          Ji, Huizhong
          Zhang, Zhili
          Dong, Enqing
        affil: https://ror.org/0207yh398 Shool of Mechanical, Electrical & Information Engineering, Shandong University, 264,209, Weihai, China
      sug:
        subj:
          Lung Radiography
          Tomography, X-Ray Computed
          Image Processing, Computer Assisted
          Human
          Deep Learning
          Algorithms
          Attention
          Neural Networks (Computer)
          Reproducibility of Results
          Sensitivity and Specificity
          Qualitative Studies
          Funding Source
      ab: Current Transformer structure utilizes the self-attention mechanism to model global contextual relevance within image, which makes an impact on medical image registration. However, the use of Transformer in handling large deformation lung CT registration is relatively straightforwardly. These models only focus on single image feature representation neglecting to employ attention mechanism to capture the across image correspondence. This hinders further improvement in registration performance. To address the above limitations, we propose a novel registration method in a cascaded manner, Cascaded Swin Deformable Cross Attention Transformer based U-shape structure (SD-CATU), to address the challenge of large deformations in lung CT registration. In SD-CATU, we introduce a Cross Attention-based Transformer (CAT) block that incorporates the Shifted Regions Multihead Cross-attention (SR-MCA) mechanism to flexibly exchange feature information and thus reduce the computational complexity. Besides, a consistency constraint in the loss function is used to ensure the preservation of topology and inverse consistency of the transformations. Experiments with public lung datasets demonstrate that the Cascaded SD-CATU outperforms current state-of-the-art registration methods (Dice Similarity Coefficient of 93.19% and Target registration error of 0.98 mm). The results further highlight the potential for obtaining excellent registration accuracy while assuring desirable smoothness and consistency in the deformed images.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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