Improved Diagnostic Performance Using Dual-Energy CT-Derived Slope Parameter Images in Crohn's Disease.
The objective of the study is to explore the image quality and diagnosis performance of the dual-energy CT-derived slope parameter images (SPI) generated by the algorithm based on the slope function in the diagnosis of Crohn's disease (CD). Seventy-six CD patients and 53 disease-free control group s...
| Publicado en: | Journal of Imaging Informatics in Medicine Vol. 38; no. 4; pp. 2312 - 2322 |
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| Autores principales: | , , , , , , , |
| Formato: | diagnostic images pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
Aug2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187278969&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187278969 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 29482925 NR3A jtl: Journal of Imaging Informatics in Medicine issn: 29482925 maglogo: N pubinfo: dt: Aug2025 vid: 38 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 187278969 187278969 187278969 10.1007/s10278-024-01330-4 187278969 ppf: 2312 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Improved Diagnostic Performance Using Dual-Energy CT-Derived Slope Parameter Images in Crohn's Disease. aug: au: Hong, Min Lin, Ziying Zhong, Hua Zhang, Yan Yang, Dan Zhong, Sihui Zhuang, Xiangrong Yue, Xin affil: https://ror.org/00mcjh785 Department of Radiology, Xiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University, No. 2999 Jinshan Road, Huli District, 361004, Xiamen, Fujian Province, China sug: subj: Radiographic Image Enhancement Evaluation Tomography, X-Ray Computed Quality Improvement Algorithms Crohn Disease Diagnosis Predictive Value of Tests Human Male Female Adult Middle Age Retrospective Design Record Review Descriptive Statistics ROC Curve Data Analysis Software kappa Statistic Friedman Test Sensitivity and Specificity Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: The objective of the study is to explore the image quality and diagnosis performance of the dual-energy CT-derived slope parameter images (SPI) generated by the algorithm based on the slope function in the diagnosis of Crohn's disease (CD). Seventy-six CD patients and 53 disease-free control group subjects who underwent dual-energy CT enterography were retrospectively collected. Portal venous phase 120kVp-like and virtual monoenergetic images at 40–100 keV (VMI40-100) were reconstructed. SPIs corresponding to the spectral curve between 40 and 100 keV (SPI40-100) were generated using Python. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of normal and abnormal intestinal walls were calculated. Image quality, noise, and contrast were independently scored by two radiologists using a 5-point scale. Four radiologists conducted CD diagnosis with three reading models (120kVp-like, 120kVp-like with optimal VMI, and 120kVp-like with SPI40-100). The diagnostic performances of the three reading models for diagnosing CD were evaluated using receiver operating characteristic (ROC) curves. The CNR in SPI40-100 was higher than in the other images (P < 0.05). The subjective evaluation showed that there was no statistical difference between the contrast of SPI40-100 and VMI40 (P > 0.05), but that of the two images was higher than the other images (P < 0.05). The scoring on the overall image quality of VMI50 was superior to that of other images (P < 0.05). The combined model of 120kVp-like with SPI40-100 had the strongest confidence (cases with high confidence: 36, 58, 49, 47 for radiologists 1, 2, 3, 4) and the highest efficiency in diagnosing CD (areas under the ROC curve: 0.973, 0.977, 0.982, 0.991 for radiologists 1, 2, 3, 4). SPI40-100 generated by the algorithm based on the slope function exhibited good image quality. The combined model of 120kVp-like with SPI40-100 could improve radiologists' diagnostic efficiency and confidence in diagnosing CD. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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