Combination of Deep and Statistical Features of the Tissue of Pathology Images to Classify and Diagnose the Degree of Malignancy of Prostate Cancer.

Prostate cancer is one of the most prevalent male-specific diseases, where early and accurate diagnosis is essential for effective treatment and preventing disease progression. Assessing disease severity involves analyzing histological tissue samples, which are graded from 1 (healthy) to 5 (severely...

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Publicado en:Journal of Imaging Informatics in Medicine Vol. 38; no. 4; pp. 2241 - 2260
Autores principales: Gao, Yan, Vali, Mahsa
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Aug2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2025
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-024-01363-9
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        atl: Combination of Deep and Statistical Features of the Tissue of Pathology Images to Classify and Diagnose the Degree of Malignancy of Prostate Cancer.
      aug:
        au:
          Gao, Yan
          Vali, Mahsa
        affil: https://ror.org/03k174p87 School of Electrical and Mechanical Engineering, Xuchang University, 461000, Xuchang, Henan, China
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        subj:
          Prostatic Neoplasms Pathology
          Deep Learning
          Early Detection of Cancer
          Prostate Pathology
          Neoplasm Staging
          Neoplasm Grading
          Human
          Male
          Image Processing, Computer Assisted
          Classification
          Descriptive Statistics
          Data Analysis Software
          Multivariate Analysis of Variance
          Post Hoc Analysis
          Male
      ab: Prostate cancer is one of the most prevalent male-specific diseases, where early and accurate diagnosis is essential for effective treatment and preventing disease progression. Assessing disease severity involves analyzing histological tissue samples, which are graded from 1 (healthy) to 5 (severely malignant) based on pathological features. However, traditional manual grading is labor-intensive and prone to variability. This study addresses the challenge of automating prostate cancer classification by proposing a novel histological grade analysis approach. The method integrates the gray-level co-occurrence matrix (GLCM) for extracting texture features with Haar wavelet modification to enhance feature quality. A convolutional neural network (CNN) is then employed for robust classification. The proposed method was evaluated using statistical and performance metrics, achieving an average accuracy of 97.3%, a precision of 98%, and an AUC of 0.95. These results underscore the effectiveness of the approach in accurately categorizing prostate tissue grades. This study demonstrates the potential of automated classification methods to support pathologists, enhance diagnostic precision, and improve clinical outcomes in prostate cancer care.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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