Autonomic and Neuroendocrine Reactivity to VR Game Exposure in Children and Adolescents with Obesity: A Factor Analytic Approach to Physiological Reactivity and Eating Behavior.

Background/Objectives: The aim was to identify patterns of autonomic and neuroendocrine reactivity to an immersive virtual reality (VR) social-emotional stressor and explore their associations with perceived stress and eating behavior. Methods: This one-group pretest–posttest study included 30 child...

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Publicado en:Nutrients Vol. 17; no. 15; pp. 2492 - 2515
Autores principales: Onita, Cristiana Amalia, Matei, Daniela-Viorelia, Trandafir, Laura-Mihaela, Petrescu-Miron, Diana, Corciova, Calin, Fuior, Robert, Manole, Lorena-Mihaela, Mihai, Bogdan-Mircea, Dascalu, Cristina-Gena, Tarcea, Monica, Bouchard, Stéphane, Mocanu, Veronica
Formato: pictorial research tables/charts Journal Article
Publicado: MDPI Aug2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2025
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        atl: Autonomic and Neuroendocrine Reactivity to VR Game Exposure in Children and Adolescents with Obesity: A Factor Analytic Approach to Physiological Reactivity and Eating Behavior.
      aug:
        au:
          Onita, Cristiana Amalia
          Matei, Daniela-Viorelia
          Trandafir, Laura-Mihaela
          Petrescu-Miron, Diana
          Corciova, Calin
          Fuior, Robert
          Manole, Lorena-Mihaela
          Mihai, Bogdan-Mircea
          Dascalu, Cristina-Gena
          Tarcea, Monica
          Bouchard, Stéphane
          Mocanu, Veronica
        affil: Center for Obesity BioBehavioral Experimental Research, Department of Morpho-Functional Sciences II (Pathophysiology), "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania
      sug:
        subj:
          Virtual Reality In Infancy and Childhood
          Virtual Reality In Adolescence
          Games
          Pediatric Obesity
          Autonomic Nervous System
          Eating Behavior
          Stress, Psychological
          Human
          Funding Source
          Descriptive Statistics
          Pretest-Posttest Design
          Male
          Female
          Child
          Adolescence
          Heart Rate Variability
          Biological Markers
          Saliva Analysis
          Visual Analog Scaling
          Questionnaires
          Hydrocortisone
          Exploratory Research
          Factor Analysis
          Child: 6-12 years
          Adolescent: 13-18 years
          Male
          Female
      ab: Background/Objectives: The aim was to identify patterns of autonomic and neuroendocrine reactivity to an immersive virtual reality (VR) social-emotional stressor and explore their associations with perceived stress and eating behavior. Methods: This one-group pretest–posttest study included 30 children and adolescents with obesity (15 boys and 15 girls), aged 8 to 17 years. The VR protocol consisted of two consecutive phases: a 5 min relaxation phase using the Forest application and a 5 min stimulation phase using a cognitively engaging VR game designed to elicit social-emotional stress. Physiological responses were measured using heart rate variability (HRV) indices and salivary stress biomarkers, including cortisol and alpha amylase. Subjective stress and eating responses were assessed via visual analogue scales (VAS) administered immediately post-exposure. The Three-Factor Eating Questionnaire (TFEQ-R21C) was used to evaluate cognitive restraint (CR), uncontrolled eating (UE), and emotional eating (EE). Results: The cortisol reactivity was blunted and may reflect both the attenuated HPA axis responsiveness characteristic of pediatric obesity and the moderate psychological challenge of the VR stressor used in this study. Two distinct autonomic response patterns were identified via exploratory factor analysis: (1) parasympathetic reactivity, associated with increased RMSSD and SDNN and decreased LF/HF, and (2) sympathetic activation, associated with increased heart rate and alpha-amylase levels and reduced RR intervals. Parasympathetic reactivity was correlated with lower perceived stress and anxiety, but also paradoxically with higher uncontrolled eating (UE). In contrast, sympathetic activation was associated with greater cognitive restraint (CR) and higher anxiety ratings. Conclusions: This study demonstrates that immersive VR game exposure elicits measurable autonomic and subjective stress responses in children and adolescents with obesity, and that individual differences in physiological reactivity are relevantly associated with eating behavior traits. The findings suggest that parasympathetic and sympathetic profiles may represent distinct behavioral patterns with implications for targeted intervention.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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