Difference between Okinawan and Dutch older adults in prefrontal brain activation.
Background: Older adults in Okinawa (Japan) are known for healthy aging and longevity. This is the first study to explore brain activation during executive functioning in Okinawan older adults in comparison to Western-European (Dutch) older adults. Methods: A total number of 80 participants were inc...
| Publicado en: | Frontiers in Aging Neuroscience pp. 1 - 14 |
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| Autores principales: | , , , , , , |
| Formato: | diagnostic images pictorial research tables/charts Journal Article |
| Publicado: |
Frontiers Media S.A.
2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187343043&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187343043 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 16634365 BG2U jtl: Frontiers in Aging Neuroscience issn: 16634365 maglogo: N pubinfo: dt: 2025 pid: 40038 pub: Frontiers Media S.A. artinfo: ui: 187343043 187343043 187343043 10.3389/fnagi.2025.1454068 187343043 ppf: 1 ppct: 13 formats: tig: atl: Difference between Okinawan and Dutch older adults in prefrontal brain activation. aug: au: Ćurčić-Blake, Branislava Futenma, Yuko Willcox, Donald Craig Tazangi, Parisa Esmaeili Wardana, Nido Dipo Ueda, Yukihiko Aleman, André affil: Cognitive Neuroscience Center, Department of Biomedical Science of Cells and Systems, University of Groningen, University Medical Center Groningen, Groningen, Netherlands sug: subj: Brain Physiology Executive Function In Old Age Prefrontal Cortex Physiology Executive Function In Old Age Task Performance and Analysis Healthy Aging Physiology Longevity Human Funding Source Netherlands Japan Male Female Middle Age Aged Aged, 80 and Over Comparative Studies Verbal Behavior Cognitive Aging Culture Neuroradiography Memory, Short Term Hemoglobins Dominance, Cerebral Descriptive Statistics Data Analysis Software Nonparametric Statistics Spectrophotometry, Infrared Frontal Lobe Physiology Neuropsychological Tests Scales Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Background: Older adults in Okinawa (Japan) are known for healthy aging and longevity. This is the first study to explore brain activation during executive functioning in Okinawan older adults in comparison to Western-European (Dutch) older adults. Methods: A total number of 80 participants were included in the study (41 from the Netherlands and 39 from Okinawa), with ages between 65 and 80 years). The groups did not differ for sex and handedness. Brain activation was measured during a visual working memory task and a verbal fluency task, for bilateral frontal cortex using functional near infrared spectroscopy (fNIRS). We investigated oxygenated hemoglobin (HbO) levels and laterality index. Results: Both groups performed within the normal range for their population. During verbal fluency, less activation in the left frontal gyrus was observed in Okinawa participants as compared to Dutch participants, and more activation in the anterior superior parts of the frontal gyrus. For the n-back task, the Okinawa group exhibited less activation in the right dorsolateral prefrontal cortex and more activation in the bilateral anterior frontal gyrus. Although laterality indices were similar for both tasks, Okinawa participants showed stronger left lateralization during category fluency. Conclusion: Our results reveal less activation of the task-relevant areas in participants from Okinawa as compared to Dutch participants. It could be hypothesized, with caution, that Okinawan older adults may need less executive processing resources to perform the task. Other differences in activation may be related to different strategy use, which may be studied in more detail in future investigations. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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