Direct Comparison of Two Commercially Available Pulsed Field Ablation Systems for Atrial Fibrillation; Procedure Characteristics and Acute Outcomes.
Background: There are few comparative studies on the everyday clinical outcomes of commercially available pulsed field ablation (PFA) systems for atrial fibrillation (AF). Objective: This study evaluates the acute efficacy and safety outcomes of the FARAPULSE™ (pentaspline catheter) and PulseSelect™...
| Publicado en: | Journal of Cardiovascular Electrophysiology Vol. 36; no. 8; pp. 1957 - 1966 |
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| Autores principales: | , , , , , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Aug2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187392162&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187392162 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10453873 GSB jtl: Journal of Cardiovascular Electrophysiology issn: 10453873 maglogo: Y pubinfo: dt: Aug2025 vid: 36 iid: 8 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 187392162 185889705 187392162 187392162 10.1111/jce.16761 187392162 ppf: 1957 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Direct Comparison of Two Commercially Available Pulsed Field Ablation Systems for Atrial Fibrillation; Procedure Characteristics and Acute Outcomes. aug: au: Abeln, Bob G. S. van der Graaf, Marisa Musat, Dan L. Gunawardene, Melanie A. Nair, Devi G. Knight, Bradley P. Wilsmore, Bradley Liebregts, Max van Dijk, Vincent F. Wijffels, Maurits C. E. F. Balt, Jippe C. Mittal, Suneet Willems, Stephan Verma, Nishant Peigh, Graham Malaty, Michael M. Boersma, Lucas V. A. affil: Department of Cardiology, St. Antonius Hospital, Nieuwegein, the Netherlands sug: subj: Atrial Fibrillation Surgery Catheter Ablation Methods Ablation Techniques Equipment and Supplies Treatment Outcomes Equipment Reliability Equipment Safety Treatment Duration Catheter Ablation Adverse Effects Postoperative Complications Human Male Female Middle Age Aged Netherlands United States Germany Australia Multicenter Studies Prospective Studies Nonexperimental Studies Retrospective Design Record Review Comparative Studies Fluoroscopy Echocardiography Descriptive Statistics Data Analysis Software T-Tests Mann-Whitney U Test Chi Square Test Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background: There are few comparative studies on the everyday clinical outcomes of commercially available pulsed field ablation (PFA) systems for atrial fibrillation (AF). Objective: This study evaluates the acute efficacy and safety outcomes of the FARAPULSE™ (pentaspline catheter) and PulseSelect™ (circular catheter) system. Methods: International, multicenter, registry on patients with paroxysmal or persistent AF, undergoing a first ablation using either PFA system between January 29th, 2024 and September 1st, 2024. Primary endpoints were electrical isolation of ablation targets, procedural characteristics and freedom from major adverse events within 30 days postprocedure. Results: A total of 402 patients were enrolled at the six participating centers, of whom 56.5% were treated with the pentaspline ablation‐catheter. Acute procedural efficacy was 100% for both groups. Use of the pentaspline ablation‐catheter was associated with significantly shorter procedural times (36.0 min [IQR 31.0; 44.0] vs. 49.0 min [IQR 41.5;76.0]) compared to the circular ablation‐catheter (p < 0.001). Major adverse events were scarce and not different between cohorts. Two patients (0.5%) experienced a stroke and one patient (0.2%) had a serious vascular access site complication. One patient had a transient ischemic attack (0.2%). Minor vascular access site complications were more common in the pentaspline catheter group (11.9% vs. 1.1%, p < 0.001). Conclusions: This study showed excellent acute efficacy and safety for both PFA‐systems. Our findings reveal shorter procedural times with the pentaspline catheter, less minor access site complications with the circular catheter, and several procedural differences between the ablation systems, often driven by operator choice. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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