Efficacy of Bihemispheric tDCS in Rehabilitation of Non-Fluent Aphasia: A Single-subject Pilot Study.

Objective: Transcranial direct current stimulation (tDCS) has emerged as a potentially effective complementary tool in rehabilitation of aphasia. However, there is no consensus regarding the optimal tDCS montage to augment language outcomes in aphasia. Against this background, the present study aime...

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Publicado en:Clinical & Experimental Health Sciences Vol. 14; no. 3; pp. 595 - 604
Autores principales: Aydın, Dilara Gamze, Bulut, Talat, Karsan, Çağdaş
Formato: clinical trial research tables/charts Journal Article
Publicado: Marmara University Sep2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2024
      vid: 14
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      pub: Marmara University
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        10.33808/clinexphealthsci.1091127
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        atl: Efficacy of Bihemispheric tDCS in Rehabilitation of Non-Fluent Aphasia: A Single-subject Pilot Study.
      aug:
        au:
          Aydın, Dilara Gamze
          Bulut, Talat
          Karsan, Çağdaş
        affil: Ha & Di Speech, Language and Counseling Center, İstanbul, Türkiye
      sug:
        subj:
          Brain Hemispheres
          Transcranial Direct Current Stimulation
          Aphasia, Broca Rehabilitation
          Treatment Outcomes
          Language Therapy
          Combined Modality Therapy
          Human
          Pilot Studies
          Stroke Patients
          Speech and Language Assessment
          Deep Brain Stimulation
          Clinical Trials
      ab: Objective: Transcranial direct current stimulation (tDCS) has emerged as a potentially effective complementary tool in rehabilitation of aphasia. However, there is no consensus regarding the optimal tDCS montage to augment language outcomes in aphasia. Against this background, the present study aimed to examine efficacy of tDCS combined with language therapy in aphasia rehabilitation and to compare two different montages. Methods: A right-handed participant suffering from chronic, non-fluent aphasia following stroke affecting the left hemisphere underwent a 5-week procedure involving tDCS coupled with language therapy. The procedure comprised two 5-day treatments of bihemispheric tDCS (over inferior frontal and posterior temporal sites determined using the international 10-20 EEG system). As part of both treatments, the left hemispheric targets were excited through anodal tDCS while simultaneously inhibiting their right-hemispheric homologues through cathodal tDCS. Baseline, post-treatment and follow-up assessments were obtained using a comprehensive language assessment tool. Results: An increase in language outcomes, particularly in repetition, was observed following the treatments. It was also found that therapy gains were more robust following bihemispheric stimulation of the posterior temporal sites compared to the inferior frontal targets. Conclusion: Bihemispheric tDCS coupled with language therapy appears to be effective in remediating language symptoms, particularly in terms of the repetition ability, in aphasia.
      pubtype: Academic Journal
      doctype:
        clinical trial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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