Pulmonary contusion volume and radiomics as predictors of early-onset pneumonia in trauma patients, a retrospective single-centre study.
Purpose: Pulmonary contusion is a common injury in thoracic trauma patients and a significant risk factor for respiratory complications such as pneumonia. This study aimed to investigate the role of pulmonary contusion volume and radiomics as predictors of pneumonia within 7 days of trauma and the d...
| Publicado en: | European Journal of Trauma & Emergency Surgery Vol. 51; no. 1; pp. 1 - 12 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
8/22/2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187496826&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187496826 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18639933 3C05 jtl: European Journal of Trauma & Emergency Surgery issn: 18639933 maglogo: N pubinfo: dt: 8/22/2025 vid: 51 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 187496826 187496826 187496826 10.1007/s00068-025-02952-1 187496826 ppf: 1 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Pulmonary contusion volume and radiomics as predictors of early-onset pneumonia in trauma patients, a retrospective single-centre study. aug: au: Gamberini, Lorenzo Astuti, Giovanna Maria Biavati, Bianca Boarato, Davide Tontodonati, Matteo Palmitessa, Irene Laruccia, Matteo Coniglio, Carlo Bertini, Alessio Orlandi, Paolo Emilio Tartaglione, Marco Allegri, Davide Bruno, Antonio affil: https://ror.org/010tmdc88 Department of Anesthesia, Intensive Care and Prehospital Emergency, Maggiore Hospital Carlo Alberto Pizzardi, Bologna, Italy sug: subj: Lung Anatomy and Histology Contusions and Abrasions Lung Injury Radiomics Pneumonia Risk Factors Trauma Complications Human Retrospective Design Nonexperimental Studies Emergency Patients Patient Admission Tomography, X-Ray Computed Emergency Service Medical Records ROC Curve Poisson Distribution Regression Multivariate Analysis Validity Thoracic Injuries Complications Questionnaires ab: Purpose: Pulmonary contusion is a common injury in thoracic trauma patients and a significant risk factor for respiratory complications such as pneumonia. This study aimed to investigate the role of pulmonary contusion volume and radiomics as predictors of pneumonia within 7 days of trauma and the degree of overlap between contused lung segments and those where pneumonia subsequently developed. Methods: This retrospective observational study included all consecutive adult trauma patients admitted to the ED with a whole-body CT scan available within 6 h from admission. The primary outcome was the occurrence of early-onset pneumonia (EOP). Data were extracted from clinical records and CT scan images were analysed for volumetric and radiomic analysis. ROC curves were built, and robust Poisson regression and extreme gradient boosting models were developed to evaluate the most influential clinical and radiologic variables. Results: Among 486 patients included, 79 (16.3%) developed early-onset pneumonia. Volumetric analysis showed higher contused lung volumes and proportions in pneumonia patients. The contusion percentage had the highest AUC (0.644) for predicting pneumonia over T-AIS and AAST lung injury scales. Multivariable analysis identified H-AIS, contusion proportion, and P/F ratio as significant predictors, with a model AUC of 0.710. Radiomic analysis improved prediction accuracy, with an extreme gradient boosting model showing an estimated out-of-sample AUC of 0.790. Conclusion: Pulmonary contusion volume is an interesting predictor of early-onset pneumonia in thoracic trauma patients. Advanced radiology techniques, including radiomics, could enhance prediction accuracy and aid in early risk stratification, potentially improving patient outcomes. Trial registration: NCT06750822, retrospectively registered. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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