Physical Function and Mobility in Older Adults Receiving Treatment for Acute Myeloid Leukemia: A Longitudinal Qualitative Study.
PURPOSE: To explore perspectives of older adults (aged 60 years or older) with acute myeloid leukemia (AML) on their physical function and mobility, assessed at three time points during treatment with a hypomethylating agent and venetoclax (HMA + VEN). PARTICIPANTS & SETTING: Participants were older...
| Publicado en: | Oncology Nursing Forum Vol. 52; no. 5; pp. 382 - 393 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Oncology Nursing Society
Sep2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187520812&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187520812 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0190535X 4F0 jtl: Oncology Nursing Forum issn: 0190535X maglogo: N pubinfo: dt: Sep2025 vid: 52 iid: 5 pid: 12496 pub: Oncology Nursing Society place: Pittsburgh, Pennsylvania artinfo: ui: 187520812 187520812 187520812 10.1188/25.ONF.382-392 187520812 ppf: 382 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Physical Function and Mobility in Older Adults Receiving Treatment for Acute Myeloid Leukemia: A Longitudinal Qualitative Study. aug: au: Ahrang Jung Crowder, Victoria Ya-Ning Chan Klemm, Dawn Tan, Kelly R. Poor, Elissa Herman Bankole, Ayomide Okanlawon Anderson, Danielle Steele Coppola, Susan Pergolotti, Mackenzi Schwartz, Todd A. Richardson, Daniel R. Bryant, Ashley Leak affil: Research specialist at the University of North Carolina (UNC) Lineberger Comprehensive Cancer Center in Chapel Hill sug: subj: Physical Mobility In Old Age Functional Status In Old Age Leukemia, Myeloid, Acute Drug Therapy Patient Attitudes In Old Age Cancer Patients In Old Age DNA Antagonists and Inhibitors Antineoplastic Agents Therapeutic Use Gerontologic Care Oncology Nursing Human Funding Source Male Female Middle Age Aged Aged, 80 and Over Prospective Studies Qualitative Studies Semi-Structured Interview Chemotherapy, Cancer Thematic Analysis Oncology Nurses North Carolina Cancer Care Facilities Purposive Sample Descriptive Statistics Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: PURPOSE: To explore perspectives of older adults (aged 60 years or older) with acute myeloid leukemia (AML) on their physical function and mobility, assessed at three time points during treatment with a hypomethylating agent and venetoclax (HMA + VEN). PARTICIPANTS & SETTING: Participants were older adults with AML (N = 17) receiving HMA + VEN at a comprehensive cancer center. Most were male and aged 64-89 years (median age = 75 years). METHODOLOGIC APPROACH: This study used a longitudinal qualitative approach with semistructured interviews at cycles 1, 2, and 7 of chemotherapy. Interviews were audio recorded, transcribed, coded, and analyzed using thematic analysis. FINDINGS: Four themes were identified: reduced mobility and limited options for physical activities (cycle 1), periodic changes in mobility and energy level (cycle 2), acceptance and adaptation to changed mobility (cycle 7), and strategies to stay active. IMPLICATIONS FOR NURSING: Substantial challenges with physical function and mobility exist for older adults undergoing treatment for AML. Oncology nurses should anticipate patient needs, provide appropriate care, and make referrals to address physical and functional needs before and during HMA + VEN treatment. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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