Family Influences on Antiretroviral Therapy Adherence in Youth with HIV in the United States: A Systematic Review.

HIV poses a significant issue in the United States and understanding how HIV-positive populations adhere to treatments, specifically with antiretroviral therapy (ART), is vital for researchers to find approaches to improve medication adherence. This systematic review aims to explore barriers that ch...

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Published in:AIDS & Behavior Vol. 29; no. 8; pp. 2621 - 2645
Main Authors: Rodriguez, Violeta J., Gessert, Miranda, Guerra, Arianna
Format: research systematic review tables/charts Journal Article
Published: Springer Nature Aug2025
Online Access:View this record in EBSCOhost
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      pub: Springer Nature
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        atl: Family Influences on Antiretroviral Therapy Adherence in Youth with HIV in the United States: A Systematic Review.
      aug:
        au:
          Rodriguez, Violeta J.
          Gessert, Miranda
          Guerra, Arianna
        affil: https://ror.org/047426m28 Department of Psychology, University of Illinois Urbana Champaign, Champaign, USA
      sug:
        subj:
          Family Role
          Antiretroviral Therapy, Highly Active In Infancy and Childhood
          Medication Compliance In Adolescence
          HIV Infections Drug Therapy
          HIV-Positive Persons In Adulthood
          Patient-Family Relations
          Stigma
          Attitude to Illness
          Stress, Psychological
          Health Services Accessibility
          Human
          Systematic Review
          Male
          Female
          Child
          Adolescence
          United States
          Adult
          Cumulative Index to Nursing & Allied Health Literature Print Index
          Medline
          Psycinfo
          Policy Making
          Holistic Care
          Child: 6-12 years
          Adolescent: 13-18 years
          Adult: 19-44 years
          Male
          Female
      ab: HIV poses a significant issue in the United States and understanding how HIV-positive populations adhere to treatments, specifically with antiretroviral therapy (ART), is vital for researchers to find approaches to improve medication adherence. This systematic review aims to explore barriers that children, adolescents, and young people (ages < 25) in the United States may face by exploring family interventions and factors influencing ART adherence. This study conducted a literature search using various databases to retrieve studies within the United States. A total of 36 studies identified family factors (n = 29) and various interventions (n = 7). Across both categories, studies indicated the critical role of family involvement in adherence outcomes. The review also identified significant barriers to ART adherence, including complex medication regimens, HIV-related stigma, and psychosocial stressors. Due to the diverse barriers, policymakers and healthcare providers should focus on a holistic approach to support ART adherence in HIV-positive youth.
      pubtype: Academic Journal
      doctype:
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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