Can machine learning be a reliable tool for predicting hematoma progression following traumatic brain injury? A systematic review and meta-analysis.

Background: Predicting hematoma progression in traumatic brain injury (TBI) is crucial for timely interventions and effective clinical management, as unchecked hematoma growth can lead to rapid neurological deterioration, increased intracranial pressure, and poor patient outcomes. Accurate risk asse...

Descripción completa

Detalles Bibliográficos
Publicado en:Neuroradiology Vol. 67; no. 7; pp. 1733 - 1750
Autores principales: Mohammadzadeh, Ibrahim, Hajikarimloo, Bardia, Eini, Pooya, Niroomand, Behnaz, Mohammadzadeh, Shahin, Habibi, Mohammad Amin, Babak, Zohre Masoumi Shahr-e, Aliaghaei, Abbas
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Springer Nature Jul2025
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187625136&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 187625136
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        00283940
        NYZ
      jtl: Neuroradiology
      issn: 00283940
      maglogo: N
    pubinfo:
      dt: Jul2025
      vid: 67
      iid: 7
      pid: 237
      pub: Springer Nature
      place: New York, New York
    artinfo:
      ui:
        187625136
        185298100
        187625136
        187625136
        10.1007/s00234-025-03657-3
        187625136
      ppf: 1733
      ppct: 17
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Can machine learning be a reliable tool for predicting hematoma progression following traumatic brain injury? A systematic review and meta-analysis.
      aug:
        au:
          Mohammadzadeh, Ibrahim
          Hajikarimloo, Bardia
          Eini, Pooya
          Niroomand, Behnaz
          Mohammadzadeh, Shahin
          Habibi, Mohammad Amin
          Babak, Zohre Masoumi Shahr-e
          Aliaghaei, Abbas
        affil: https://ror.org/034m2b326 Skull Base Research Center, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
      sug:
        subj:
          Brain Injuries Complications
          Hematoma Physiopathology
          Disease Progression Risk Factors
          Machine Learning Algorithms
          Prediction Algorithms
          Prediction Models
          Risk Assessment
          Human
          Systematic Review
          Meta Analysis
          Embase
          PubMed
          Descriptive Statistics
          Sensitivity and Specificity
          Decision Support Systems, Clinical
          Diagnosis, Computer Assisted
          Odds Ratio
          Confidence Intervals
          Artificial Intelligence
          Predictive Value of Tests
          Cerebral Hemorrhage Risk Factors
          Hematoma, Epidural, Cranial Risk Factors
          Hematoma, Subdural Risk Factors
          Deep Learning
          Decision Making, Clinical
      ab: Background: Predicting hematoma progression in traumatic brain injury (TBI) is crucial for timely interventions and effective clinical management, as unchecked hematoma growth can lead to rapid neurological deterioration, increased intracranial pressure, and poor patient outcomes. Accurate risk assessment enables proactive therapeutic strategies, minimizing secondary brain damage and improving survival rates. Methods: This study evaluated to assess the performance of artificial intelligence (AI) algorithms, including machine learning (ML) and deep learning (DL), in forecasting risk of hematoma progression. Comprehensive searches across Embase, Scopus, Web of Science and PubMed identified relevant studies, with data extracted on algorithm metrics such as sensitivity, specificity, and area under the curve (AUC). Results: 1,240 studies screened, five out of them met the inclusion criteria, evaluating various AI models. The meta-analysis revealed a pooled sensitivity and specificity was 0.76 [95% CI: 0.67–0.83], 0.84 [95% CI: 0.78–0.89], positive and negative likelihood ratio was 4.82 [95% CI: 3.51–6.61] 0.29 [95% CI: 0.21–0.39], diagnostic score was 2.82 [95% CI: 2.33–3.32], diagnostic odds ratio was16.85 [95% CI: 10.29–27.59] and an AUC of 0.88 [95% CI: 0.85–0.90]. Among the evaluated algorithms, XGBoost has the best predictive performance with an accuracy of 91%. Integrating radiomics and clinical features in these models considerably improved the predictive outcomes. Conclusion: The current results demonstrated the potential of AI-based models to improve hematoma progression prediction for TBI patients, thereby supporting more effective clinical decision-making. Further research should aim to standardize datasets and diversify patient populations to improve model applicability and reliability.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N