Association Between Turn Impairments and Cognitive Function in Parkinson Disease.
Objective: To investigate the association of turn parameters with cognitive status in patients with Parkinson disease (PD) and determine the value of turn performance in distinguishing PD‐related cognitive impairment (CI) from normal cognition (NC). Methods: This study recruited 168 patients with PD...
| Publicado en: | Aging Medicine Vol. 8; no. 4; pp. 286 - 294 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Aug2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187635504&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187635504 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 24750360 LE57 jtl: Aging Medicine issn: 24750360 maglogo: N pubinfo: dt: Aug2025 vid: 8 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 187635504 187524519 187635504 187635504 10.1002/agm2.70033 187635504 ppf: 286 ppct: 8 formats: tig: atl: Association Between Turn Impairments and Cognitive Function in Parkinson Disease. aug: au: Xu, Shanhu Kong, Linlin Liu, Xiaoli Lou, Yue Gu, Luyan Xu, Qiuhan Tan, Xun Pu, Jiali Zhang, Baorong affil: Department of Neurology, Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China sug: subj: Parkinson Disease Complications Cognition Gait Disorders, Neurologic Cognition Disorders Risk Factors Risk Assessment Walking Task Performance and Analysis Human Male Female Cross Sectional Studies Nonexperimental Studies Descriptive Statistics Clinical Assessment Tools Parametric Statistics Mann-Whitney U Test Chi Square Test Data Analysis Software Quality of Life Age Factors Hallucinations Severity of Illness Educational Status Depression Sex Factors Funding Source Scales Male Female ab: Objective: To investigate the association of turn parameters with cognitive status in patients with Parkinson disease (PD) and determine the value of turn performance in distinguishing PD‐related cognitive impairment (CI) from normal cognition (NC). Methods: This study recruited 168 patients with PD, including 102 patients with NC and 66 patients with CI. The participants performed 180° turn performance trials during the Timed Up and Go walk and 360° turn trials in place using the MATRIX wearable system. Four turn parameters, namely, turn duration, step count, mean turn angular velocity (MAV), and peak turn angular velocity (PAV), were evaluated. Mini‐Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) were performed to evaluate cognitive function. Results: In comparison with the PD‐NC group, the PD‐CI group showed significantly higher turn duration and step counts and lower MAV and PAV during both 180° and 360° turns. The four turn parameters were significantly correlated with MMSE and MoCA scores after correction for age and educational level. Regression models suggested that the risk of PD‐CI was associated with step counts and MAV during 360° turns. The area under the curve values of the step counts and MAV during 360° turns for distinguishing PD‐CI from PD‐NC were 0.781 and 0.789, respectively. Conclusion: Our findings indicate that turn performance is associated with cognitive status in patients with PD. Assessment of 360° turn characteristics during routine clinic visits would provide a better understanding of CI status in individuals with PD. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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