Volunteers Needed: Understanding African Americans' Perceptions of Clinical Trials and Intentions to Participate.
Goal: African Americans lack participation in clinical trials, and therefore, are underrepresented in medical initiatives that can provide life-saving treatment. This research examines the attitudes, beliefs, and perceptions of African Americans toward participation in clinical trials. Methods: Rese...
| Publicado en: | Journal of Healthcare Management Vol. 70; no. 5; pp. 317 - 337 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Sep/Oct2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187727117&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187727117 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10969012 37I jtl: Journal of Healthcare Management issn: 10969012 maglogo: N pubinfo: dt: Sep/Oct2025 vid: 70 iid: 5 pid: 5086 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 187727117 187727117 187727117 10.1097/JHM-D-24-00137 187727117 ppf: 317 ppct: 20 formats: tig: atl: Volunteers Needed: Understanding African Americans' Perceptions of Clinical Trials and Intentions to Participate. aug: au: Ricks, Joe M. Porter III, McDowell Kemp, Elyria affil: Division of Business, Xavier University of Louisiana, New Orleans, Louisiana sug: subj: African Americans Psychosocial Factors Intention Research Subjects Psychosocial Factors Clinical Trials Patient Participation Psychosocial Factors Patient Attitudes Health Knowledge Human Funding Source United States Louisiana Male Female Adult Adolescence Middle Age Aged Aged, 80 and Over Cross Sectional Studies Questionnaires Factor Analysis Motivation Risk Assessment Models, Theoretical Attitude to Risk Health Behavior Educational Status Decision Making Descriptive Statistics Data Analysis Software Confidence Intervals Multiple Regression Structural Equation Modeling Post Hoc Analysis Ajzen-Fishbein Theory of Reasoned Action Adult: 19-44 years Adolescent: 13-18 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Goal: African Americans lack participation in clinical trials, and therefore, are underrepresented in medical initiatives that can provide life-saving treatment. This research examines the attitudes, beliefs, and perceptions of African Americans toward participation in clinical trials. Methods: Researchers conducted a survey using a representative sample of African Americans in the United States (n = 1,260). Structural equation modeling was used to analyze the data. Principal Findings: Findings indicate that behavioral beliefs about clinical trials are positively related to attitudes about participating in clinical trials. Furthermore, attitudes are positively related to intentions to participate in clinical trials. Participation in clinical trials is also dictated by social influence. Results indicate that what "important others" think about participation in clinical trials is positively related to trial participation; however, risk perceptions are negatively related to trial participation. Findings reveal that gender and educational attainment moderate risk perceptions. African American women and those with less educational attainment possess risk perceptions, which negatively influence their intention to participate in clinical trials. Practical Applications: This research highlights how behavioral beliefs and attitudes are positively linked to participation intentions, while subjective norms further reinforce the influence of social pressures on decision-making. Importantly, risk perceptions serve as a significant barrier to participation, particularly among African American women and individuals with lower educational attainment. These findings point to the need for targeted interventions that address specific concerns and build trust through culturally informed, accessible communication. By developing communication strategies that enhance positive beliefs, leverage community influence, and reduce perceived risks, research and healthcare communities can take meaningful steps toward fostering inclusion and trust. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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