Lifting Limits: The Impact of Strength Training in Down Syndrome—A Systematic Review and Meta‐Analysis.
Background: People with Down syndrome (DS) may exhibit several musculoskeletal disorders, including alterations in muscle tone and activation. Strength training could mitigate the loss of muscle strength and, therefore, improve strength values in this population. Additionally, it may influence healt...
| Published in: | Journal of Intellectual Disability Research Vol. 69; no. 9; pp. 781 - 795 |
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| Main Authors: | , , , , |
| Format: | research systematic review tables/charts Journal Article |
| Published: |
Wiley-Blackwell
Sep2025
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187843864&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187843864 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09642633 EUL jtl: Journal of Intellectual Disability Research issn: 09642633 maglogo: Y pubinfo: dt: Sep2025 vid: 69 iid: 9 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 187843864 185804824 187843864 187843864 10.1111/jir.13259 187843864 ppf: 781 ppct: 14 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Lifting Limits: The Impact of Strength Training in Down Syndrome—A Systematic Review and Meta‐Analysis. aug: au: Iglesias‐Díaz, Luis López‐Ortiz, Susana García‐Chico, Celia Santos‐Lozano, Alejandro González‐Lázaro, Javier affil: Department of Health Sciences, Miguel de Cervantes European University, Valladolid, Spain sug: subj: Down Syndrome Muscle Strengthening Disease Attributes Training Effect (Physiology) Grip Strength Task Performance and Analysis Physical Activity Body Composition Biological Markers Bone Density Physical Endurance Human Funding Source Systematic Review Meta Analysis PubMed Descriptive Statistics Scales Chi Square Test Confidence Intervals Functional Status Muscle Strength Resistance Training Intellectual Disability Exercise ab: Background: People with Down syndrome (DS) may exhibit several musculoskeletal disorders, including alterations in muscle tone and activation. Strength training could mitigate the loss of muscle strength and, therefore, improve strength values in this population. Additionally, it may influence health‐related outcomes such as physical function, body composition and biochemical markers. Objective: This systematic review and meta‐analysis of randomised controlled trials (RCTs) aimed to analyse the characteristics and effects of strength training in people with DS. Methods: A search was conducted from inception to 22 April 2025. The methodological quality of the included RCTs was assessed using the 15‐item Tool for the assEssment of Study qualiTy and reporting in EXercise (TESTEX). In addition, the risk of bias was assessed using the Cochrane's risk of bias 2 (RoB2). Results: A total of 10 RCTs (n = 233 participants) were included in the systematic review, of which three (n = 111 participants) could be meta‐analysed. The pooled effect showed statistically significant benefits for upper (mean difference [MD] = 5.66 kg, 95% CI 2.42–8.91) and lower (MD = 20.43 kg, 95% CI 1.76–39.10) body strength. The TESTEX scores for most RCTs ranged from 3 to 12 points. The risk of bias analysis indicated that eight RCTs had a low risk of bias, whereas the remaining studies were classified as high risk. Conclusion: Strength training may significantly improve muscle strength in people with DS. However, further research is needed to assess the long‐term effects on physical function, body composition and biochemical markers. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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