Gait Recovery in Patients with Stroke with Severe Motor Damage: The Prognostic Role of Sensory Pathway Preservation.

Background: The role of sensory pathways in gait recovery remains unclear. We hypothesized that preservation of the somatosensory pathway may play a key role in gait recovery in patients with stroke and severe motor pathway impairment. Objective: This study aimed to investigate the impact of preserv...

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Publicado en:NeuroRehabilitation Vol. 57; no. 2; pp. 264 - 275
Autores principales: Ju, Yeonwoo, Yoo, Yeun Jie, Yoon, Mi-Jeong, Hong, Bo Young, Lee, Jong In, Lim, Seong Hoon
Formato: diagnostic images research tables/charts Journal Article
Publicado: Sage Publications Inc. Sep2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2025
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      pub: Sage Publications Inc.
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        atl: Gait Recovery in Patients with Stroke with Severe Motor Damage: The Prognostic Role of Sensory Pathway Preservation.
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          Ju, Yeonwoo
          Yoo, Yeun Jie
          Yoon, Mi-Jeong
          Hong, Bo Young
          Lee, Jong In
          Lim, Seong Hoon
        affil: Department of Rehabilitation Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
      sug:
        subj:
          Stroke Patients
          Stroke Rehabilitation
          Gait
          Recovery
          Severity of Injury
          Motor Skills
          Evoked Potentials, Somatosensory
          Cerebral Cortex
          Stroke Prognosis
          Sensory Motor Integration
          Neural Pathways
          Thalamus
          Human
          Retrospective Design
          Cross Sectional Studies
          Magnetic Resonance Imaging
          Multiple Logistic Regression
          Functional Status
          South Korea
          Physical Therapy
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          Adult
          Male
          Female
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          Chi Square Test
          T-Tests
          Wilcoxon Rank Sum Test
          Univariate Statistics
          Multivariate Statistics
          Odds Ratio
          Confidence Intervals
          Data Analysis Software
          Funding Source
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      ab: Background: The role of sensory pathways in gait recovery remains unclear. We hypothesized that preservation of the somatosensory pathway may play a key role in gait recovery in patients with stroke and severe motor pathway impairment. Objective: This study aimed to investigate the impact of preserving the somatosensory pathway, spinothalamic tract (STT), and superior thalamic radiation (STR) on gait recovery in patients with chronic stroke and severe damage to motor pathways. Methods: This retrospective cross-sectional study included 85 patients and investigated the association between functional ambulation categories and the integrity of sensory pathways, as represented by fractional anisotropy values. Diffusion tensor imaging was performed to assess the integrity of the corticospinal tract (CST), cortico-ponto-cerebellar tract, STT, and STR 6 months after stroke. Results: Multivariable logistic regression analysis revealed that severe damage to the CST with the STT preserved yielded an odds ratio of 8.49 (p = 0.030) for functional gait, compared to when both tracts were damaged. Conclusions: Somatosensory pathways may play a critical role in gait recovery for patients with chronic stroke and severe motor tract damage. Preserving the somatosensory pathway could facilitate gait recovery in patients with severe motor pathway damage, offering valuable insights for future stroke rehabilitation strategies.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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