Efficacy of manual therapy on central sensitization in subjects with chronic low back pain: A systematic review and meta-analysis.
The present study aims to determine the effects of joint manual therapy (MT) on central sensitization (CS) in individuals with Chronic low back pain (CLBP). A systematic search was performed in PubMed, Scopus, ScienceDirect, Embase/Ovid, CINHAL, CENTRAL, Web of Science and PEDRO, clinicaltrials.gov...
| Publicado en: | Journal of Bodywork & Movement Therapies Vol. 44; pp. 672 - 686 |
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| Autores principales: | , , , |
| Formato: | research systematic review Journal Article |
| Publicado: |
Churchill Livingstone, Inc.
Oct2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187944848&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187944848 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13608592 8II jtl: Journal of Bodywork & Movement Therapies issn: 13608592 maglogo: N pubinfo: dt: Oct2025 vid: 44 pid: 1242 pub: Churchill Livingstone, Inc. artinfo: ui: 187944848 187944848 187944848 10.1016/j.jbmt.2025.06.020 187944848 ppf: 672 ppct: 14 formats: tig: atl: Efficacy of manual therapy on central sensitization in subjects with chronic low back pain: A systematic review and meta-analysis. aug: au: Tabatabaei, Abbas Molaei, Farzan Mangdow, Mustapha Sharma, Neena K. affil: CORR LabDepartment of Physical Therapy, Rehabilitation Science, and Athletic Training, School of Health Professions, University of Kansas Medical Center, Kansas City, KS, USA sug: subj: Low Back Pain Rehabilitation Chronic Pain Rehabilitation Manual Therapy Nervous System Physiology Training Effect (Physiology) Evaluation Human Systematic Review Meta Analysis PubMed Embase CINAHL Database Physiotherapy Evidence Database Descriptive Statistics Confidence Intervals ab: The present study aims to determine the effects of joint manual therapy (MT) on central sensitization (CS) in individuals with Chronic low back pain (CLBP). A systematic search was performed in PubMed, Scopus, ScienceDirect, Embase/Ovid, CINHAL, CENTRAL, Web of Science and PEDRO, clinicaltrials.gov , and ICTRP. All studies included the effect of joint MT on CS in various people with CLBP. The assessment of quality and data synthesis was completed. Standardized mean difference and 95 % confidence intervals were used to conduct a meta-analysis. The systematic review and meta-analysis revealed a small overall effect size of 0.01 (95 % CI: −0.27 to 0.29), indicating a negligible impact of joint MT on CS in individuals with CLBP. A small but significant effect (SMD:0.31 (95 % CI: 0.00, 0.63)) of MT was observed on peripheral sensitization. No significant effect of MT was observed on pressure pain thresholds on various body areas, TS or CPM. Therefore, the neurophysiological effects of joint MT on CS remain unclear. Further research to needed, utilizing a variety of measures to understand the role of MT in managing CS symptoms in individuals with CLBP. pubtype: Academic Journal doctype: meta analysis research systematic review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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