Interaction Between Age and Task Demand on Brain Connectivity Associated With Mastication.
Background: Sensorimotor processing is critical to the ageing brain and geriatric health. Masticatory performance (MP) is key to the systemic health of older individuals. Neuroimaging research has revealed a potential link between brain functional connectivity (FC) and MP. Using the masticatory pert...
| Publicado en: | Journal of Oral Rehabilitation Vol. 52; no. 10; pp. 1757 - 1768 |
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| Autores principales: | , |
| Formato: | diagnostic images pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Oct2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187948954&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187948954 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0305182X ERZ jtl: Journal of Oral Rehabilitation issn: 0305182X maglogo: Y pubinfo: dt: Oct2025 vid: 52 iid: 10 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 187948954 185335361 187948954 187948954 10.1111/joor.14036 187948954 ppf: 1757 ppct: 11 formats: tig: atl: Interaction Between Age and Task Demand on Brain Connectivity Associated With Mastication. aug: au: Lin, Chia‐Shu Kao, Wei‐Chieh affil: Department of Dentistry, National Yang Ming Chiao Tung University, Taipei City, Taiwan sug: subj: Mastication Physiology Brain Physiology Age Factors Functional Connectivity Methods Task Performance and Analysis Funding Source Human Male Female Adult Middle Age Aged Aged, 80 and Over Cross Sectional Studies Magnetic Resonance Imaging Multiple Regression One-Way Analysis of Variance Descriptive Statistics Data Analysis Software Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Background: Sensorimotor processing is critical to the ageing brain and geriatric health. Masticatory performance (MP) is key to the systemic health of older individuals. Neuroimaging research has revealed a potential link between brain functional connectivity (FC) and MP. Using the masticatory perturbation task (MPT), we investigated the FC associated with MP under different conditions of task demand and age groups. Methods: Thirty‐four older‐age (OA, ≥ 65 years), 26 middle‐aged (MA, between 40 and 64 years) and 42 younger‐age (YA, < 40 years) participants were recruited for assessment of the MPT, and structural and resting‐state (rs) functional magnetic resonance imaging (MRI). Analyses of seed‐based connectivity and FC networks were conducted to investigate the rs‐FC associated with MP in the baseline condition (without perturbation) and the perturbation condition (with perturbation) of MPT. Results: (A) In the baseline condition, OA participants with better MP showed higher rs‐FC between the cerebellum and primary sensorimotor cortices. (B) In the perturbation condition, OA participants with better MP showed higher rs‐FC between the middle frontal gyrus and the primary somatosensory cortex, and MA participants with better MP showed higher rs‐FC between the supplementary motor area and the caudate nucleus. (C) The network analysis revealed that the pattern of rs‐FC related to MP differed between age groups and task conditions. In the perturbation condition, YA participants with better MP showed higher rs‐FC outside the sensorimotor network. Conclusion: The findings provide novel evidence demonstrating an interaction between age and task demand on rs‐FC associated with MP. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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