Adaptation and Implementation of Self-System Therapy for Older Adults with Advanced Lung Cancer: Pilot Trial Results.
Simple Summary: Lung cancer is a highly prevalent disease that disproportionately affects adults aged 65 and older. Existing interventions addressing the psychological burden of lung cancer are frequently inaccessible and inadequately tailored to this population's unique needs. The aim of this pilot...
| Publicado en: | Cancers Vol. 17; no. 17; pp. 2809 - 2821 |
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| Autores principales: | , , , , , |
| Formato: | clinical trial research tables/charts Journal Article |
| Publicado: |
MDPI
Sep2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=187985488&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 187985488 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20726694 B74B jtl: Cancers issn: 20726694 maglogo: N pubinfo: dt: Sep2025 vid: 17 iid: 17 pid: 97109 pub: MDPI artinfo: ui: 187985488 187985488 187985488 10.3390/cancers17172809 187985488 ppf: 2809 ppct: 12 formats: tig: atl: Adaptation and Implementation of Self-System Therapy for Older Adults with Advanced Lung Cancer: Pilot Trial Results. aug: au: Ramos, Katherine Ayaz, Aliza Riley, Jennie Faircloth, Kaylee Porter, Laura S. Strauman, Timothy J. affil: Department of Psychiatry & Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA sug: subj: Lung Neoplasms Therapy Neoplasm Invasiveness Lung Neoplasms Psychosocial Factors Psychosocial Intervention Treatment Outcomes Evaluation Support, Psychosocial Evaluation Psychological Distress Prevention and Control Human Male Female Aged Clinical Trials Implementation Science Protocols Neoplasm Staging Pilot Studies Patient Compliance Patient Satisfaction Depression Prevention and Control Conceptual Framework Emotions Psychological Well-Being Quality of Life Functional Status Treatment Duration Telehealth Interviews Purposive Sample Scales Exploratory Research T-Tests Wilcoxon Signed Rank Test Confidence Intervals Self-Efficacy Age Factors Sex Factors Race Factors Marital Status Income Educational Status Thematic Analysis Content Analysis Descriptive Statistics Data Analysis Software Funding Source Aged: 65+ years Male Female ab: Simple Summary: Lung cancer is a highly prevalent disease that disproportionately affects adults aged 65 and older. Existing interventions addressing the psychological burden of lung cancer are frequently inaccessible and inadequately tailored to this population's unique needs. The aim of this pilot trial was to assess the feasibility, acceptability, and preliminary signal of Self-System Therapy (SST) for distress reduction in advanced lung cancer. Findings from this study may inform future interventions and supportive care strategies for older adults living with advanced cancer by fostering resilience, reducing distress, and improving quality of life. Background/Objectives: Advanced lung cancer is a highly distressing disease that negatively impacts older adults. Supportive care interventions designed for this population are scarce and often inaccessible due to competing demands and transportation access. We adapted and refined an evidence-based treatment, Self-System Therapy (SST), to address the unmet needs of older adults with advanced cancer. Methods: Guided by principles of implementation science, we conducted patient interviews, focus groups, and user testing to refine our new SST for the lung cancer (SST-LC) protocol. We then conducted a single-arm pilot trial (clinicaltrials.gov NCT04057196) for patients aged 65+ and above with Stage III or IV lung cancer (N = 30). Benchmarks for acceptability, feasibility, and preliminary changes in outcome measures were assessed. Results: Our study met the desired recruitment goals and demonstrated high treatment adherence rates (89%) and satisfaction rates (85%), indicating that SST-LC was feasible and well-received. Participants also showed reductions in distress and depression, and improvements in emotional and functional well-being from baseline to post-intervention, with effects mostly maintained at follow-up. Physical well-being, social well-being, and quality of life showed smaller, non-significant changes. Feedback from participants also suggested that SST enhanced their resilience and ability to cope with cancer-related challenges, but also indicated a preference for fewer sessions. Conclusions: SST for older adults living with advanced lung cancer is feasible and acceptable. Moreover, this supportive care intervention shows promise in addressing psychological distress, emotional well-being, and functional well-being in older adults. Future research will include testing the efficacy of SST in a larger randomized controlled trial. pubtype: Academic Journal doctype: clinical trial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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