COVID-19 mortality waves in ASEAN driven by demographic, policy, and cardiovascular factors.

Introduction: ASEAN, comprising 10 nations and the world's seventh-largest economy, effectively mitigated COVID-19 through trade, healthcare, and cultural integration despite political disparities. Nevertheless, rapid policy shifts in COVID-19 control, combined with varying vaccination rates, notabl...

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Publicado en:Discover Public Health Vol. 22; no. 1; pp. 1 - 14
Autores principales: Nguyen, Ngoc Huy, Le, Son Dinh Thanh, Bui, Ha Thi Thu, Hoang, Viet Quoc, Do, Cuong Cao, Trang, Vu Thi Thu
Formato: research tables/charts Journal Article
Publicado: Springer Nature 9/21/2025
Acceso en línea:Ver este registro en EBSCOhost
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      place: New York, New York
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        10.1186/s12982-025-00898-8
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        atl: COVID-19 mortality waves in ASEAN driven by demographic, policy, and cardiovascular factors.
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          Nguyen, Ngoc Huy
          Le, Son Dinh Thanh
          Bui, Ha Thi Thu
          Hoang, Viet Quoc
          Do, Cuong Cao
          Trang, Vu Thi Thu
        affil: Phutho Department of Health, Phutho, Vietnam
      sug:
        subj:
          COVID-19 Mortality
          COVID-19 Prevention and Control
          Sociodemographic Factors Evaluation
          Public Policy
          Cardiovascular Diseases Mortality
          International Agencies
          Human
          Male
          Female
          Aged
          Aged, 80 and Over
          Retrospective Design
          Record Review
          COVID-19 Vaccines
          Immunization
          Multiple Linear Regression
          Descriptive Statistics
          Confidence Intervals
          Economic Status
          Public Health Infrastructure
          Policy Making
          Health Care Delivery
          Southeast Asians
          Health Policy
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Introduction: ASEAN, comprising 10 nations and the world's seventh-largest economy, effectively mitigated COVID-19 through trade, healthcare, and cultural integration despite political disparities. Nevertheless, rapid policy shifts in COVID-19 control, combined with varying vaccination rates, notably influenced COVID-19 mortality waves (CMW). The distinct outbreak patterns among countries underscore the crucial need to accurately identify factors related to daily new COVID-19 deaths (DNCD). Methods: The retrospective study examined Our World in Data database to assess factors affecting DNCD in ASEAN from vaccination start to May 1st, 2024. Joinpoint regression analysis, performed using Joinpoint Trend Analysis Software 5.1.0, identified bell-shaped patterns in CMW, while a Weighted Least Squares (WLS) model and Bayesian Model Averaging, executed in R 4.3.1, determined the primary predictors influencing DNCD. Results: Joinpoint regression identified that 5 out of 10 countries experienced their CMW, lasting 767 days and resulting in 236,098 deaths. The WLS model, with a strong model fit (R2 = 92.09%), reveals significant associations. Each 1% increase in COVID-19 vaccination (– 0.96; 95% CI – 1.19; – 0.72), each $1000 increase in GDP per capita (– 10.35; 95% CI – 11.09; – 9.61), each 1% increase in stringency index (– 3.89; 95%CI – 4.28;-3.51), and each additional hospital bed per thousand people (– 53.83; 95% CI – 60.50; – 47.16) are associated with lower DNCD. Conversely, increases in active cases (2.33; 95% CI 2.26;2.40) and cardiovascular death rate (0.90; 95% CI 0.85; 0.96) correlate with higher DNCD. Conclusion: The study highlights vaccination, economic stability, healthcare infrastructure, and stringency measures in reducing DNCD. Policymakers should prioritize vaccination and healthcare improvements while monitoring active cases and cardiovascular health for future preparedness.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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