Qualitative evaluation to improve participant engagement and retention in remote COVID-19 treatment trials.
Clinical trials, although recognized as the gold standard for scientific research, encounter various challenges with participant recruitment and retention. Yet, given the surge in global research endeavors during the COVID-19 pandemic, mass recruitment and retention were needed to ensure study power...
| Publicado en: | Discover Public Health Vol. 22; no. 1; pp. 1 - 16 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
9/24/2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=188242177&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 188242177 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 30050774 NM7Z jtl: Discover Public Health issn: 30050774 maglogo: N pubinfo: dt: 9/24/2025 vid: 22 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 188242177 188242177 188242177 10.1186/s12982-025-00970-3 188242177 ppf: 1 ppct: 15 formats: tig: atl: Qualitative evaluation to improve participant engagement and retention in remote COVID-19 treatment trials. aug: au: Perez-Brumer, Amaya Balasa, Rebecca Doshi, Aarti S. Bowra, Andrea Brisson, Julien Philbin, Morgan M. Doan, Thuy Oldenburg, Catherine E. affil: https://ror.org/03dbr7087 Dalla School of Public Health, University of Toronto, M5T 3M7, Toronto, ON, Canada sug: subj: Clinical Trials COVID-19 Research Subject Recruitment Research Subject Retention Motivation Human Male Female Adult Middle Age Aged Aged, 80 and Over Prospective Studies Qualitative Studies Comparative Studies Descriptive Statistics Purposive Sample Semi-Structured Interview Questionnaires Funding Source Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Clinical trials, although recognized as the gold standard for scientific research, encounter various challenges with participant recruitment and retention. Yet, given the surge in global research endeavors during the COVID-19 pandemic, mass recruitment and retention were needed to ensure study power. While participant engagement in clinical research has been investigated, there is limited literature underscoring motivations for participation in COVID-19 clinical trials conducted remotely. To address this gap, we conducted a longitudinal, qualitative evaluation study of participant engagement and retention in a remote, COVID-19 clinical trial. In-depth, semi-structured interviews were conducted between December 2020-March 2021 (timepoint 1; n = 19) and January–February 2022 (timepoint 2; n = 11) to gain insights from participants regarding their experiences, motivations, and challenges with clinical trial engagement during the COVID-19 pandemic. Findings identified several factors described to increase participant engagement, including perceived contribution to the greater good, protecting oneself and others, and gaining improved access to healthcare. Further, key themes underscoring the enhancement of retention, such as perceived trial-related challenges and recommendations for future studies, were also identified. Findings underscore the utility of embedding qualitative methods within clinical trials, and how they contribute to a broader understanding of factors influencing participation in COVID-19 trials while providing valuable insights to enhancing recruitment and retention strategies. Consequently, this study provides essential knowledge aimed at optimizing participant engagement and retention in clinical trials, thereby advancing our comprehension of and response to research mobilization during unprecedented events. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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