Development of a Machine Learning-Based Nutrition-Related Surgical Risk Assessment Model for Older Patients with Gastrointestinal Malignancies.

Older patients with gastrointestinal cancer are at a high risk of postoperative complications; however, no accurate preoperative assessment is available. This study developed a prognostic model that leveraged machine learning and multidimensional clinical data to predict postoperative complications...

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Publicado en:Nutrition & Cancer Vol. 77; no. 10; pp. 1121 - 1132
Autores principales: Yin, Shishu, Liu, Xu, Cao, Xianglong, Cui, Jian, Shi, Jinxin, Ma, Fuhai, Ma, Tianming, An, Qi, Yu, Tao, Li, Zijian, Zhao, Gang
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd 2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2025
      vid: 77
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        10.1080/01635581.2025.2552461
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        atl: Development of a Machine Learning-Based Nutrition-Related Surgical Risk Assessment Model for Older Patients with Gastrointestinal Malignancies.
      aug:
        au:
          Yin, Shishu
          Liu, Xu
          Cao, Xianglong
          Cui, Jian
          Shi, Jinxin
          Ma, Fuhai
          Ma, Tianming
          An, Qi
          Yu, Tao
          Li, Zijian
          Zhao, Gang
        affil: Department of General Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P.R. China
      sug:
        subj:
          Machine Learning
          Prediction Models
          Risk Assessment
          Nutritional Assessment
          Malnutrition Risk Factors
          Postoperative Complications Risk Factors
          Stomach Neoplasms Surgery
          Colorectal Neoplasms Surgery
          Funding Source
          China
          Human
          Retrospective Design
          Random Assignment
          ROC Curve
          Data Analysis Software
          Body Mass Index
          Hemoglobins
          Albumins
          Comorbidity
          Patient Safety
          Quality Improvement
          Hospitalization of Older Persons
          Scales
          Activities of Daily Living
          Questionnaires
          Prediction Algorithms
          Male
          Female
          Aged
          Aged, 80 and Over
          Random Forest
          Boosting Machine Learning Algorithms
          Support Vector Machine
          Logistic Regression
          Descriptive Statistics
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Older patients with gastrointestinal cancer are at a high risk of postoperative complications; however, no accurate preoperative assessment is available. This study developed a prognostic model that leveraged machine learning and multidimensional clinical data to predict postoperative complications in older patients. This study assessed 365 older patients with gastrointestinal cancer who underwent radical surgery at Beijing Hospital. Patients were randomly allocated to training and test sets (7:3 ratio). Multiplex machine learning was used for feature selection and model development. The efficacies of the models were assessed using receiver operating characteristic curves. An imbalance rfsrc + ranger model (IRM) was created using the "shiny" R package. All statistical analyses were performed using R software. The overall rate of postoperative complications was 19.2%. IRM was the most accurate among the 361 models developed using 19 machine learning algorithms and 19 sets of clinical features. Body mass index was the most important variable for predicting postoperative complications in these patients, followed by hemoglobin level, albumin level, and surgical approach. This study developed a nutrition-related surgical risk assessment model that includes malnutrition, comorbidities, and surgical approaches to improve the outcome of older patients with gastrointestinal malignancies, aiding in managing preoperative risk factors and improving surgical safety.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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