Minimal clinically important difference and substantial clinical benefits for single- and dual-task timed up and go test following motor-cognitive training in Parkinson's disease.
Objective To establish substantial clinical benefits (SCB) and minimal clinically important differences (MCIDs) for both the single-task and dual-task timed up and go (TUG) tests in people with Parkinson's disease (PwPD). Design Prospective pre–post intervention study evaluating the effects of combi...
| Publicado en: | Age & Ageing Vol. 54; no. 9; pp. 1 - 10 |
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| Autores principales: | , , , , , , , , |
| Formato: | Artículo |
| Publicado: |
Oxford University Press / USA
Sep2025
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=188359312&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 188359312 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00020729 AGA jtl: Age & Ageing issn: 00020729 maglogo: N pubinfo: dt: Sep2025 vid: 54 iid: 9 pid: 622 pub: Oxford University Press / USA artinfo: ui: 188359312 10.1093/ageing/afaf241 ppf: 1 ppct: 9 formats: tig: atl: Minimal clinically important difference and substantial clinical benefits for single- and dual-task timed up and go test following motor-cognitive training in Parkinson's disease. aug: au: Taghizadeh, Ghorban Eissazade, Negin Fereshtehnejad, Seyed-Mohammad Sharabiani, Parvaneh Taghavi Azar Shati, Mohsen Mortazavi, Seyede Salehe Habibi, Sayed Amir Hasan SalemiJuybari, Maryam Mehdizadeh, Maryam affil: Rehabilitation Research Center, Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran Geriatric Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, Iran Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran Brain and Cognition Clinic, Institute for Cognitive Sciences Studies, Tehran, Iran Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, Stockholm, Sweden Division of Neurology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada Department of Occupational Therapy, Shafa Yahyaeian Hospital, Iran University of Medical Sciences, Tehran, Iran Mental Health Research Center, Psychosocial Health Research Institute, Iran University of Medical Sciences, Tehran, Iran School of Public Health, Department of Epidemiology, Iran University of Medical Sciences, Tehran, Iran Department of Neurology, Rasool Akram Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran su: United Kingdom Motor ability Patients Randomized controlled trials Anxiety Psychological tests Mental depression Dual-task paradigm Cognitive testing Receiver operating characteristic curves Exercise therapy Statistical sampling Standing position Fatigue (Physiology) Parkinson's disease Treatment effectiveness Descriptive statistics Longitudinal method Pre-tests & post-tests Rehabilitation centers Walking Geriatric assessment Medical rehabilitation Intraclass correlation Sitting position Neuropsychological tests Health outcome assessment Cognitive rehabilitation Sensitivity & specificity (Statistics) sug: subj: Motor ability Patients Randomized controlled trials Anxiety Psychological tests Mental depression United Kingdom Other Individual and Family Services Psychiatric and Substance Abuse Hospitals Residential Mental Health and Substance Abuse Facilities Marketing Research and Public Opinion Polling Dual-task paradigm Cognitive testing Receiver operating characteristic curves Exercise therapy Statistical sampling Standing position Fatigue (Physiology) Parkinson's disease Treatment effectiveness Descriptive statistics Longitudinal method Pre-tests & post-tests Rehabilitation centers Walking Geriatric assessment Medical rehabilitation Intraclass correlation Sitting position Neuropsychological tests Health outcome assessment Cognitive rehabilitation Sensitivity & specificity (Statistics) keyword: functional mobility get up and go test minimal clinically important difference mobility older people parkinson disease roc curve substantial clinical benefit timed up and go test functional mobility get up and go test minimal clinically important difference mobility older people parkinson disease roc curve substantial clinical benefit timed up and go test ab: Objective To establish substantial clinical benefits (SCB) and minimal clinically important differences (MCIDs) for both the single-task and dual-task timed up and go (TUG) tests in people with Parkinson's disease (PwPD). Design Prospective pre–post intervention study evaluating the effects of combined motor–cognitive training. Setting Rehabilitation centers. Participants One hundred fifteen PwPD, with a mean age of 61.33 ± 13.01 years. Interventions Dual-task motor-cognitive training. Main outcome measures Time taken to complete the single-task and dual-task TUG tests, recorded both before and after the intervention. MCIDs were calculated using the anchor-based and distribution-based methods. SCB was assessed using the receiver operating characteristic (ROC) curve analysis. Results The anchor-based MCIDs for the single-task and dual-task TUG tests ranged from −0.71 to −1.27, and − 0.82 to −1.81, respectively. The distribution-based MCIDs for the single-task and dual-task TUG tests ranged from −1.07 to −1.14, and − 1.65 to −1.98, respectively. The SCB for both the single-task and dual-task TUG tests was determined to be less than −2.04. Conclusion This investigation provides critical insights into interpreting changes in functional mobility in PwPD, facilitating informed clinical interventions and enhancing research planning initiatives. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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