Effects of exercise-cognitive dual-task training on cognitive frailty in older adults: a randomized controlled trial.

Objective: This study aims to investigate the effects of exercise-cognitive dual-task training on frailty status, cognitive function, physical performance, and dual-task cognitive load in older adults with Cognitive frailty (CF) over a 16-week intervention period. Methods: This randomized controlled...

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Publicado en:Frontiers in Aging Neuroscience pp. 1 - 10
Autores principales: Lai, Xiaoxing, Zhu, Hongwei, Cai, Yonghua, Chen, Baoyu, Li, Yang, Du, Hongdi, Zhang, Liping, Wang, Wenwen, Li, Shuxian, Huo, Xiaopeng
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Frontiers Media S.A. 2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2025
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      pub: Frontiers Media S.A.
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        10.3389/fnagi.2025.1639245
        188368371
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        atl: Effects of exercise-cognitive dual-task training on cognitive frailty in older adults: a randomized controlled trial.
      aug:
        au:
          Lai, Xiaoxing
          Zhu, Hongwei
          Cai, Yonghua
          Chen, Baoyu
          Li, Yang
          Du, Hongdi
          Zhang, Liping
          Wang, Wenwen
          Li, Shuxian
          Huo, Xiaopeng
        affil: Department of Neurology, Peking Union Medical College Hospital, Beijing, China
      sug:
        subj:
          Cognition Disorders Therapy
          Frailty Syndrome Therapy
          Task Performance and Analysis
          Therapeutic Exercise
          Cognitive Therapy
          Training Effect (Physiology)
          Physical Performance
          Community Living In Old Age
          Treatment Outcomes Evaluation
          Human
          Female
          Male
          Aged
          Aged, 80 and Over
          Randomized Controlled Trials
          Random Assignment
          Control Group
          Community Health Centers
          China
          Balance, Postural
          Gait Analysis
          Walking
          Clinical Assessment Tools
          Scales
          Health Education
          Sample Size Determination
          Cognition Evaluation
          Comparative Studies
          T-Tests
          Fisher's Exact Test
          Data Analysis Software
          Descriptive Statistics
          Funding Source
          Aged: 65+ years
          Aged, 80 & over
          Female
          Male
      ab: Objective: This study aims to investigate the effects of exercise-cognitive dual-task training on frailty status, cognitive function, physical performance, and dual-task cognitive load in older adults with Cognitive frailty (CF) over a 16-week intervention period. Methods: This randomized controlled trial enrolled older adults with CF at community health service center in Chaoyang District, Beijing, between February and March 2024. Participants were randomly assigned to either the dual-task training group or the health education group in a 1:1 ratio. The dual-task training group received an exercise-cognitive dual-task training program, while the health education group received information on CF, including its symptoms, risk factors, and non-pharmacological prevention and treatment strategies. The primary outcomes were frailty status, while the secondary outcomes included cognitive function, balance and gait function, walking ability, and dual-task cognitive load. Results: A total of 72 participants (35 males) were enrolled, including 36 individuals (mean age: 74.81 ± 8.23 years, 17 males, mean BMI: 21.38 ± 2.83 kg/m2) in the dual-task training group, and 36 individuals (mean age: 76.50 ± 7.75 years, 18 males, mean BMI: 22.18 ± 2.12 kg/m2) in the health education group. Participants (n = 72) were 75.66 ± 7.9 years old; 48.6% (35/72) were male and 51.4% (37/72) were female. Following the intervention, the dual-task training group exhibited significant improvements compared to the health education group in the Tilburg Frailty Index (5.14 ± 0.99 vs. 7.36 ± 1.07, p < 0.001) and Montreal Cognitive Assessment scores (27.25 ± 2.41 vs. 23.47 ± 1.87, p < 0.001). Additionally, the dual-task training group demonstrated superior outcomes in the Performance-Oriented Mobility Assessment (POMA) scores (24.64 ± 5.50 vs. 17.39 ± 4.38, p < 0.001), Time Up and Go Test (TUGT) indicators (10.66 ± 1.76 vs. 12.01 ± 2.21, p < 0.05), and cognitive load measures (all p < 0.05). Conclusion: Exercise-cognitive dual-task training may effectively improve frailty status, cognitive function, physical performance, and dual-task cognitive load in older adults with CF, suggesting its potential for broader application in this population. Clinical trial registration: http://www.chictr.org.cn/ , ChiCTR2400080105.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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