Safety, pharmacokinetics, and pharmacodynamics of Dexmedetomidine two-phase flow atomization in healthy subjects: a randomized, parallel study.

Background: In this study, we aimed to compare the sedative effects, pharmacokinetics (PKs), and safety of dexmedetomidine (DEX) administered using a two-phase flow atomization device with those of conventional intranasal drop-based administration in healthy volunteers. Methods: This prospective, pa...

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Detalles Bibliográficos
Publicado en:BMC Anesthesiology Vol. 25; no. 1; pp. 1 - 10
Autores principales: Lian, Yujun, Luo, Huanqi, Yang, Zhijing, He, Jiadi, Chen, Haozhu, Sun, Yanyan
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: BioMed Central 10/1/2025
Acceso en línea:Ver este registro en EBSCOhost