Randomized Controlled Trial of a Couples-Based HIV Intervention for Transgender Women and Their Partners: Findings from the "It Takes Two" Project.

"It Takes Two" is a couples-based HIV prevention program designed for transgender women and their partners. The aim of this project is to alleviate HIV vulnerability by enhancing communication, improving shared goals, and decreasing relationship stigma. From November 2019 to November 2022, we conduc...

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Publicado en:AIDS & Behavior Vol. 29; no. 11; pp. 3544 - 3557
Autores principales: Gamarel, Kristi E., Operario, Don, Stein, Ellen S., Pollack, Lance M., Neilands, Torsten B., McCree, Breonna, Johnson, Jack, Correll-King, Wesley M., Olem, David, Johnson, Mallory O., Sevelius, Jae M.
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Springer Nature Nov2025
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Randomized Controlled Trial of a Couples-Based HIV Intervention for Transgender Women and Their Partners: Findings from the "It Takes Two" Project.
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          Gamarel, Kristi E.
          Operario, Don
          Stein, Ellen S.
          Pollack, Lance M.
          Neilands, Torsten B.
          McCree, Breonna
          Johnson, Jack
          Correll-King, Wesley M.
          Olem, David
          Johnson, Mallory O.
          Sevelius, Jae M.
        affil: https://ror.org/00jmfr291 Department of Health Behavior and Health Equity, University of Michigan School of Public Health, 1415 Washington Heights, 48109-2029, Ann Arbor, MI, USA
      sug:
        subj:
          HIV Infections Prevention and Control
          Trans Women Psychosocial Factors
          Sexual Partners Psychosocial Factors
          Couples Counseling
          Stigma Prevention and Control
          Disease Susceptibility Prevention and Control
          Communication
          Goals and Objectives
          Program Evaluation
          Human
          Male
          Female
          Adult
          Descriptive Statistics
          Randomized Controlled Trials
          Random Assignment
          Self Report
          Linear Regression
          Logistic Regression
          Funding Source
          Scales
          California
          HIV Education
          Problem Solving
          Unsafe Sex
          Sexually Transmitted Diseases
          Adult: 19-44 years
          Male
          Female
      ab: "It Takes Two" is a couples-based HIV prevention program designed for transgender women and their partners. The aim of this project is to alleviate HIV vulnerability by enhancing communication, improving shared goals, and decreasing relationship stigma. From November 2019 to November 2022, we conducted a randomized controlled trial with 52 couples (104 individuals). Participants were randomized into one of two groups: the intervention group received four 1-hour counseling sessions, while the control group received educational videos. Due to the COVID-19 pandemic, 60% of participants took part in a fully digital trial, including telehealth counseling. Assessments were conducted at baseline and at 3, 6, 9, and 12 months. We analyzed the outcomes using multilevel random coefficient models. While the intervention did not significantly impact HIV vulnerability, communication, or shared goals, there were reductions in relationship stigma among partners of transgender women at 3- (Cohen's d = 0.54), 6- (Cohen's d = 0.57), and 12-months (Cohen's d = 0.72) post-intervention. These findings highlight the importance of addressing relationship stigma and involving partners in HIV prevention efforts to promote the health of transgender women.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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