Parental Psychological Control, the Parent–Adolescent Relationship, and Non-suicidal Self-Injury Among Chinese Adolescents: The Moderating Effect of the Oxytocin Receptor Gene rs53576 Polymorphism.

Parental psychological control (PPC) is associated with adolescent non-suicidal self-injury (NSSI); however, its underlying mechanisms have not been extensively investigated. Considering that genetic and environmental factors interactively influence adolescent development, this study examined whethe...

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Publicado en:Child Psychiatry & Human Development Vol. 56; no. 5; pp. 1279 - 1287
Autores principales: Wang, Huahua, Deng, Yuting, Li, Meijin, Tao, Zhiyuan, Yu, Chengfu
Formato: Artículo
Publicado: Springer Nature Oct2025
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2025
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      pub: Springer Nature
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        10.1007/s10578-023-01646-2
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        atl: Parental Psychological Control, the Parent–Adolescent Relationship, and Non-suicidal Self-Injury Among Chinese Adolescents: The Moderating Effect of the Oxytocin Receptor Gene rs53576 Polymorphism.
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          Wang, Huahua
          Deng, Yuting
          Li, Meijin
          Tao, Zhiyuan
          Yu, Chengfu
        affil:
          https://ror.org/05ar8rn06 Department of Psychology, School of Education, Guangzhou University, 510006, Guangzhou, Guangdong, China
          Zhangbian Primary School, 511446, Guangzhou, Guangdong, China
          https://ror.org/01kq0pv72 School of Psychology, South China Normal University, 510631, Guangzhou, Guangdong, China
      su:
        Self-injurious behavior
        Parent-teenager relationships
        Control (Psychology)
        Social influence
        Genetic variation
        Oxytocin receptors
        Mediation (Statistics)
      sug:
        subj:
          Self-injurious behavior
          Parent-teenager relationships
          Control (Psychology)
          Social influence
          Genetic variation
          Oxytocin receptors
          Mediation (Statistics)
      keyword:
        Adolescent
        Non-suicidal self-injury (NSSI)
        OXTR gene rs53576 polymorphism
        Parent–adolescent relationship
        Parental psychological control
        Psychology and Cognitive Sciences Psychology Medical and Health Sciences Public Health and Health Services
        Adolescent
        Non-suicidal self-injury (NSSI)
        OXTR gene rs53576 polymorphism
        Parent–adolescent relationship
        Parental psychological control
        Psychology and Cognitive Sciences Psychology Medical and Health Sciences Public Health and Health Services
      ab: Parental psychological control (PPC) is associated with adolescent non-suicidal self-injury (NSSI); however, its underlying mechanisms have not been extensively investigated. Considering that genetic and environmental factors interactively influence adolescent development, this study examined whether the parent–adolescent relationship mediated the link between PPC and adolescent NSSI, and whether this mediating process was moderated by the oxytocin receptor gene rs53576 polymorphism (OXTR rs53576). Participants comprised 673 adolescents (Mean = 12.81 years, SD = 0.48 years) who completed questionnaires regarding PPC, the parent–adolescent relationship, and NSSI. DNA was extracted from each participant's saliva samples. The results indicated that the positive association between PPC and adolescent NSSI was mediated by the parent–adolescent relationship. Moreover, this indirect link was stronger for adolescents with AA homozygotes of OXTR rs53576 than for those with the GG or AG genotype. These findings extend our understanding of the association between PPC and adolescent NSSI and suggest that a simultaneous focus on PPC, the parent–adolescent relationship, and OXTR rs53576 may favor NSSI interventions.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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