The Effect of Exercise Intervention on Cognitive Function and Quality of Life With Autism Spectrum Disorder: A Systematic Review and Meta-Analysis.

Background: Physical exercise may confer benefits on cognitive function and quality of life in children with autism spectrum disorder (ASD). However, the evidence has not been co mprehensively synthesized. This study aimed to investigate the effect of exercise intervention on cognitive function and...

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Publicado en:Actas Espanolas de Psiquiatria Vol. 53; no. 4; pp. 839 - 857
Autores principales: Cai, Benben, Miao, Yingying, Zhao, Jiajia, Ying, Xiaoming, Lin, Weiqiang
Formato: Artículo
Publicado: Maria Lopez-Ibor 2025
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Acceso en línea:Ver este registro en EBSCOhost
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        atl: The Effect of Exercise Intervention on Cognitive Function and Quality of Life With Autism Spectrum Disorder: A Systematic Review and Meta-Analysis.
      aug:
        au:
          Cai, Benben
          Miao, Yingying
          Zhao, Jiajia
          Ying, Xiaoming
          Lin, Weiqiang
        affil: Department of Pediatrics, Taizhou First People’s Hospital (Huangyan Hospital, Wenzhou Medical University), 318020 Taizhou, Zhejiang, China.
      su:
        Quality of life
        Autism spectrum disorders
        Physical activity
        Cognitive ability
        School children
        Therapeutics
      sug:
        subj:
          Quality of life
          Autism spectrum disorders
          Physical activity
          Cognitive ability
          School children
          Therapeutics
      keyword:
        behavioral aspects
        children with autism spectrum disorder (ASD)
        motor skills
        physical exercise
        quality of life
        sleep
        social cognition
        social communication
      ab: Background: Physical exercise may confer benefits on cognitive function and quality of life in children with autism spectrum disorder (ASD). However, the evidence has not been co mprehensively synthesized. This study aimed to investigate the effect of exercise intervention on cognitive function and quality of life with ASD, and provide evidence to support the scientific use of exercise interventions in practice. Methods: We systematically searched major databases from inception to November 2023 for randomized trials and observational studies examining exercise interventions in children with ASD. Mean differences (MDs) with 95% confidence intervals (CIs) were calculated using random-effects models. Heterogeneity was assessed using the I² statistic. Risk of bias was evaluated with the Cochrane tool. Results: Fourteenth studies were included. Metaanalysis of 8 randomized trials found a small but significant effect of exercise on social communication (MD: 1.42, 95% CI: 0.21 to 2.6322, p = 0.02, I² = 29%). The effect on social cognition was also significant (MD: 1.99, 95% CI: 0.18 to 3.80, p = 0.03, I² = 0%). Influential analysis identified 2 studies as outliers. Leave-one-out analysis showed meta-analysis conclusions were robust. The included studies consistently demonstrated benefits of exercise on sleep, behavioral aspects, motor skills, quality of life, and other outcomes. Conclusions: This meta-analysis provides evidence that exercise interventions may improve core symptoms and functional outcomes in children with ASD. However, small sample sizes and heterogeneity indicate cautious interpretation. Further adequately powered trials are needed to establish optimal exercise programs for managing ASD.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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      custom: Copyright of Actas Espanolas de Psiquiatria is the property of Maria Lopez-Ibor and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use.
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