| Sumario: | This article examines the application of the A3 problem-solving methodology, one of the foundations of lean quality improvement, within a level 1 trauma center. Using the example of central line–associated bloodstream infections (CLABSIs), this article demonstrates how the A3's structured approach supports systematic and sustainable process improvement. The A3's standardized format and emphasis on data-driven decision-making, combined with bottom-up staff engagement, enabled a significant reduction in CLABSIs and improved staff knowledge. The findings highlight the A3's adaptability and effectiveness in addressing complex health care challenges, encouraging a culture of continuous improvement, and contributing to enhanced patient safety and reduced health care costs.
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