| Sumario: | Objective To screen the influencing factors for first recanalization in patients with acute large artery occlusive cerebral infarction after Solitaire stent multi-mode endovascular treatment. Methods The 100 patients with acute large artery occlusive cerebral infarction who received Solitaire stent multi-mode endovascular treatment in The First People's Hospital of Qinzhou from January 2020 to June 2022 were enrolled. The modified Thrombolysis in Cerebral Infarction (mTICI) was used to evaluate the recanalization. The National Institutes of Health Stroke Scale (NIHSS) was used to evaluate the severity of neurological deficits, and the Alberta Stroke Program Early CT Score (ASPECT) was used to evaluate degree of cerebral ischemia before and 24h after surgery. The modified Rankin Scale (mRS) was used to evaluate the neurological functional prognosis. Univariate and multivariate Logistic regression analyses were conducted to screen the influencing factors for the first recanalization. Results A total of 100 patients were divided into the first recanalization group (n=50) and the non-first recanalization group (n=50) according to whether they reached the mTICI blood flow grading standard (mTICI≥2b). Logistic regression analysis showed that middle cerebral artery occlusion (OR=0.233, 95%CI: 0.133-0.446; P=0.015), more collateral circulation compensation (OR=0.342, 95%CI: 0.203-0.538; P=0.024), the ASPECT score increased 24h after surgery (OR=0.223, 95%CI: 0.078-0.707; P=0.000), the mRS score decreased 90 d after surgery (OR=0.539, 95%CI: 0.194-0.884; P=0.002) were protective factors for the first recanalization after Solitaire stent multi-mode endovascular treatment. The frequency of thrombectomy increased (OR=3.347, 95%CI: 1.118-5.576; P=0.002), prolonged time from onset to recanalization (OR=4.997, 95%CI: 1.798-14.947; P=0.009), the NIHSS score increased 24h after the surgery (OR=3.038, 95%CI: 2.173-4.587; P=0.000) were risk factors for the non-first recanalization after Solitaire stent multi-mode endovascular treatment. Conclusions The first recanalization after Solitaire stent multi-mode endovascular treatment is affected by multiple factors. During the clinical diagnosis and treatment process, adjusting the intervention and treatment measures according to the relevant influencing factors is of great significance for improving the clinical efficacy.
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