Morphological comparison between artificial intelligence-driven and manual CAD design in single tooth restoration: a preliminary study.

Objective: The integration of artificial intelligence (AI) into CAD/CAM workflows has revolutionized dental prosthetics manufacturing, yet its morphological trueness compared to manual design remains underexplored. Materials and methods: This study evaluated 30 single-tooth restoration cases from 30...

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Publicado en:BMC Oral Health Vol. 25; no. 1; pp. 1 - 8
Autores principales: Xie, Bing-ying, He, Xiao, Hu, Li, Guo, Shan-lin, Chen, Jun-lan, Zhang, Jing, Shen, Xiao-qing, Geng, Yuan-ming, Li, Wei
Formato: pictorial research tables/charts Journal Article
Publicado: BioMed Central 10/17/2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 10/17/2025
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      pub: BioMed Central
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        10.1186/s12903-025-07004-z
        188778122
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        atl: Morphological comparison between artificial intelligence-driven and manual CAD design in single tooth restoration: a preliminary study.
      aug:
        au:
          Xie, Bing-ying
          He, Xiao
          Hu, Li
          Guo, Shan-lin
          Chen, Jun-lan
          Zhang, Jing
          Shen, Xiao-qing
          Geng, Yuan-ming
          Li, Wei
        affil: https://ror.org/01vjw4z39 Department of Stomatology, Zhujiang Hospital, Southern Medical University, 253 Gongyedadao Road, 510282, Guangzhou, China
      sug:
        subj:
          Artificial Intelligence
          Computer-Aided Design
          Dental Restoration, Permanent
          Dental Prosthesis Design
          Human
          Funding Source
          Comparative Studies
          Descriptive Statistics
          Data Analysis Software
          Paired T-Tests
          Two-Tailed Test
          Wilcoxon Signed Rank Test
          Workflow
          Information Science
          Image Processing, Computer Assisted
          Time Factors
          Reproducibility of Results
      ab: Objective: The integration of artificial intelligence (AI) into CAD/CAM workflows has revolutionized dental prosthetics manufacturing, yet its morphological trueness compared to manual design remains underexplored. Materials and methods: This study evaluated 30 single-tooth restoration cases from 30 patients. For each case, the original clinically-approved designs were used as reference. AI designs (3Shape Automate) were compared to manual designs created by a technician (3Shape Dental System™). Morphological trueness was evaluated through 3D deviation analysis. Global surface deviations (RMSE) were compared using the Wilcoxon signed-rank test, and maximum discrepancies were compared with a paired Student's t-test, with significance set at p < 0.05. Results: While AI demonstrated batch-processing efficiency, 6.7% of cases (2/30) with suboptimal preparation geometries required manual intervention. No significant difference was found in global surface deviation between AI (median = 79.8 μm) and manual designs (median = 68.6 μm; p = 0.1056). However, AI designs produced significantly greater maximum discrepancies (mean = 225.0 μm) compared to manual designs (mean = 184.4 μm; p = 0.0243). Conclusion: These findings validate AI's viability for routine restoration design but emphasize the necessity of case selection protocols and algorithm improvements for dynamic occlusion modeling to ensure comprehensive clinical adoption.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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