A systematic review on volumetric analysis in orbital MRI.

Aim: Volumetric analysis of orbital soft tissues using magnetic resonance imaging (MRI) offers valuable diagnostic and pathophysiological insights into orbital inflammation, trauma, and tumors. However, the optimal MRI protocols and post-processing methods for specific conditions remain unclear. Met...

Descripción completa

Detalles Bibliográficos
Publicado en:Neuroradiology Vol. 67; no. 9; pp. 2533 - 2550
Autores principales: Degraeve, Michiel, Ninclaus, Virginie, Deferm, Julie, Brusselaers, Nele, Jacobs, Reinhilde, Willaert, Robin
Formato: research systematic review tables/charts Journal Article
Publicado: Springer Nature Sep2025
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=188799172&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 188799172
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        00283940
        NYZ
      jtl: Neuroradiology
      issn: 00283940
      maglogo: N
    pubinfo:
      dt: Sep2025
      vid: 67
      iid: 9
      pid: 237
      pub: Springer Nature
      place: New York, New York
    artinfo:
      ui:
        188799172
        187744590
        188799172
        188799172
        10.1007/s00234-025-03734-7
        188799172
      ppf: 2533
      ppct: 17
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: A systematic review on volumetric analysis in orbital MRI.
      aug:
        au:
          Degraeve, Michiel
          Ninclaus, Virginie
          Deferm, Julie
          Brusselaers, Nele
          Jacobs, Reinhilde
          Willaert, Robin
        affil: https://ror.org/00cv9y106 Ghent University, Ghent, Belgium
      sug:
        subj:
          Magnetic Resonance Imaging Evaluation
          Orbit Anatomy and Histology
          Orbital Diseases Physiopathology
          Orbital Diseases Diagnosis
          Human
          Systematic Review
          PubMed
          Medline
          Cochrane Library
          Descriptive Statistics
          Optic Nerve
          Lacrimal Apparatus
          Image Processing, Computer Assisted
          Oculomotor Muscles
          Sensitivity and Specificity
          Medical Practice, Evidence-Based
          Checklists
          Orbit Pathology
          Inflammation
          Trauma
          Orbital Neoplasms
      ab: Aim: Volumetric analysis of orbital soft tissues using magnetic resonance imaging (MRI) offers valuable diagnostic and pathophysiological insights into orbital inflammation, trauma, and tumors. However, the optimal MRI protocols and post-processing methods for specific conditions remain unclear. Methods: A systematic search was performed in PubMed/MEDLINE, Web of Science, and Cochrane Library for all studies published before November 2024. This review adhered to PRISMA guidelines and was prospectively registered. Primary outcomes included (i) MRI acquisition parameters, (ii) post-processing volumetry techniques, and (iii) regions of interest (ROI). Secondary outcomes assessed clinical relevance and validation methods. Results: From 4323 records, 35 articles were included. Significant heterogeneity was observed regarding MRI acquisition and post-processing techniques. Volumetry most commonly targeted extraocular muscles and orbital fat, although definitions of ROI borders varied widely. Analysis of the globe, orbital cavity, optic nerve, and lacrimal gland was less frequent. Validation of volumetric methods was reported in only a minority of studies. Conclusions: Accurate interpretation of volumetric data requires careful consideration of technical variables. Standardization of acquisition protocols, validated segmentation methods, and automated volumetry approaches are essential for enhancing reproducibility and clinical applicability. This systematic review provides a comprehensive framework for future research in orbital MRI volumetry.
      pubtype: Academic Journal
      doctype:
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N