Adverse childhood experiences as a risk factor for depression-overweight comorbidity in adolescence and young adulthood.
The comorbidity of depression and overweight is a manifestation of mental-physical multimorbidity, a marker of complex healthcare needs. We sought to examine how adverse childhood experiences (ACEs) are associated with depression-overweight comorbidity in the period of adolescence and early adulthoo...
| Published in: | European Journal of Public Health Vol. 35; no. 5; pp. 896 - 903 |
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| Main Authors: | , , |
| Format: | research tables/charts Journal Article |
| Published: |
Oxford University Press / USA
Oct2025
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=188809828&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 188809828 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11011262 BHW jtl: European Journal of Public Health issn: 11011262 maglogo: N pubinfo: dt: Oct2025 vid: 35 iid: 5 pid: 622 pub: Oxford University Press / USA artinfo: ui: 188809828 188809828 188809828 10.1093/eurpub/ckaf102 188809828 ppf: 896 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Adverse childhood experiences as a risk factor for depression-overweight comorbidity in adolescence and young adulthood. aug: au: Kilpi, Fanny Soares, Ana Goncalves Howe, Laura D affil: MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom sug: subj: Depression Risk Factors Depression Risk Factors Pediatric Obesity Risk Factors Obesity Risk Factors Adverse Childhood Experiences Comorbidity Age Factors Sex Factors Socioeconomic Factors Risk Assessment Human Funding Source Male Female Adolescence Young Adult Prospective Studies Self Report Body Mass Index Emotional Abuse Sexual Abuse Multiple Logistic Regression Descriptive Statistics Colleges and Universities Parents Questionnaires Adolescent: 13-18 years Male Female ab: The comorbidity of depression and overweight is a manifestation of mental-physical multimorbidity, a marker of complex healthcare needs. We sought to examine how adverse childhood experiences (ACEs) are associated with depression-overweight comorbidity in the period of adolescence and early adulthood, and the extent to which associations are sensitive to age, sex, and socioeconomic background. Using data from 4734 adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort, we estimated relative risk ratios (RRR) for the associations of multiple ACEs (physical, emotional, and sexual abuse, emotional neglect, being bullied, parental substance abuse, violence between parents, parental criminal conviction, parental separation, parental mental illness, or suicide) with depression only, overweight only or their comorbidity at ages 17 and 24. We tested whether associations differed by sex and socioeconomic background, indicated by parental education. Most ACEs were associated with depression-overweight comorbidity, and there was a dose–response relationship whereby a greater number of ACEs was associated with greater risk, and this continued from adolescence to young adulthood. Some ACEs associations with comorbidity appeared to be influenced by sex: at age 17, females had stronger associations for parental separation and mental health problems, and at age 24, sexual abuse had a stronger association in males. We did not find evidence that the sensitivity to ACEs varied by parental education. ACEs across childhood are associated with depression and depression-overweight comorbidity in late adolescence, which indicates their potential impact on the early manifestation of complex healthcare needs. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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