Data-Oriented Octree Inverse Hierarchical Order Aggregation Hybrid Transformer-CNN for 3D Medical Segmentation.

The hybrid CNN-transformer structures harness the global contextualization of transformers with the local feature acuity of CNNs, propelling medical image segmentation to the next level. However, the majority of research has focused on the design and composition of hybrid structures, neglecting the...

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Publicado en:Journal of Imaging Informatics in Medicine Vol. 38; no. 5; pp. 3168 - 3182
Autores principales: Li, Yuhua, Jiang, Shan, Yang, Zhiyong, Wang, Lixiang, Wang, Liwen, Zhou, Zeyang
Formato: diagnostic images equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Oct2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2025
      vid: 38
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      pub: Springer Nature
      place: New York, New York
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        188953391
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        atl: Data-Oriented Octree Inverse Hierarchical Order Aggregation Hybrid Transformer-CNN for 3D Medical Segmentation.
      aug:
        au:
          Li, Yuhua
          Jiang, Shan
          Yang, Zhiyong
          Wang, Lixiang
          Wang, Liwen
          Zhou, Zeyang
        affil: https://ror.org/012tb2g32 Mechanical Engineering Department, Tianjin University, No. 135, Yaguan Road, Haihe Education Park, Jinnan District, 300350, Tianjin City, China
      sug:
        subj:
          Imaging, Three-Dimensional
          Convolutional Neural Networks
          Conceptual Framework
          Image Interpretation, Computer Assisted
          Deep Learning
          Human
          Funding Source
          Algorithms
          Neural Networks (Computer)
          Computer Simulation
          Models, Theoretical
          Reproducibility of Results
          Qualitative Studies
          Quantitative Studies
          Tomography, X-Ray Computed
          Descriptive Statistics
          Data Analysis Software
          Wilcoxon Rank Sum Test
          Wilcoxon Signed Rank Test
      ab: The hybrid CNN-transformer structures harness the global contextualization of transformers with the local feature acuity of CNNs, propelling medical image segmentation to the next level. However, the majority of research has focused on the design and composition of hybrid structures, neglecting the data structure, which enhance segmentation performance, optimize resource efficiency, and bolster model generalization and interpretability. In this work, we propose a data-oriented octree inverse hierarchical order aggregation hybrid transformer-CNN (nnU-OctTN), which focuses on delving deeply into the data itself to identify and harness potential. The nnU-OctTN employs the U-Net as a foundational framework, with the node aggregation transformer serving as the encoder. Data features are stored within an octree data structure with each node computed autonomously yet interconnected through a block-to-block local information exchange mechanism. Oriented towards multi-resolution feature data map learning, a cross-fusion module has been designed that associates the encoder and decoder in a staggered vertical and horizontal approach. Inspired by nnUNet, our framework automatically adapts network parameters to the dataset instead of using pre-trained weights for initialization. The nnU-OctTN method was evaluated on the BTCV, ACDC, and BraTS datasets and achieved excellent performance with dice score coefficient (DSC) 86.95, 92.82, and 90.61, respectively, demonstrating its generalizability and effectiveness. Cross-fusion module effectiveness and model scalability are validated through ablation experiments on BTCV and Kidney. Extensive qualitative and quantitative experimental results demonstrate that nnU-OctTN achieves high-quality 3D medical segmentation that has competitive performance against current state-of-the-art methods, providing a promising idea for clinical applications.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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