Randomized Controlled Trial Testing an HIV/STI Prevention Intervention Among People Leaving Incarceration Who Were Assigned Male at Birth, Have Sex with Men and A Substance Use Disorder.
HIV disproportionately impacts minoritized individuals, particularly those of intersectional minoritized identities. Incarceration disproportionately impacts minoritized individuals as well, and increases HIV risk, in part due to its disruption to people's lives, social networks, and access to care....
| Publicado en: | AIDS & Behavior Vol. 29; no. 12; pp. 3806 - 3822 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Springer Nature
Dec2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=189055909&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 189055909 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10907165 G1T jtl: AIDS & Behavior issn: 10907165 maglogo: N pubinfo: dt: Dec2025 vid: 29 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 189055909 186487352 189055909 189055909 10.1007/s10461-025-04818-4 189055909 ppf: 3806 ppct: 16 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Randomized Controlled Trial Testing an HIV/STI Prevention Intervention Among People Leaving Incarceration Who Were Assigned Male at Birth, Have Sex with Men and A Substance Use Disorder. aug: au: Schrode, Katrina M. Edwards, Gabriel G. Moghanian, Brandon Weiss, Robert E. Reback, Cathy J. McWells, Charles Hilliard, Charles L. Harawa, Nina T. affil: https://ror.org/038x2fh14 Department of Psychiatry, Charles R. Drew University of Medicine and Science, Los Angeles, CA, USA sug: subj: HIV Infections Prevention and Control Sexually Transmitted Diseases Prevention and Control Men Who Have Sex With Men Psychosocial Factors Trans Women Psychosocial Factors Substance Use Disorders Therapy Prisoners Correctional Facilities Mobile Applications Utilization Health Screening Human Funding Source Male Female Randomized Controlled Trials Random Assignment Needs Assessment Wellness Health Care Delivery, Integrated Pre-Exposure Prophylaxis HIV Infections Risk Factors Substance Use Disorders Complications Criminal Justice Community Reintegration Smartphone Utilization Peer Group Support, Psychosocial Descriptive Statistics Data Analysis Software Referral and Consultation Male Female ab: HIV disproportionately impacts minoritized individuals, particularly those of intersectional minoritized identities. Incarceration disproportionately impacts minoritized individuals as well, and increases HIV risk, in part due to its disruption to people's lives, social networks, and access to care. We developed MEPS, a 6-month intervention designed to holistically support HIV prevention in men who have sex with men and transgender women leaving incarceration. We tested MEPS in a 1:1 randomized controlled trial with 208 individuals. All participants received a needs assessment and personalized wellness plan, followed by either standard of care or the MEPS intervention. MEPS integrated support from a Peer Mentor, incentives for engagement in social and health services, and a mobile app. Participants completed baseline assessments and follow-up assessments at 3, 6, and 9 months. We tested for changes in PrEP use using a group-based trajectory model, for changes in HIV and STI testing, frequent substance use and recidivism using logistic mixed models, and for changes in HCV testing and in having a regular place for care using Poisson models. MEPS participants were significantly more likely than control participants to be among those who used PrEP [AOR (95% CI) = 3.8 (1.8, 8.0)]. Recent HIV testing in the MEPS arm remained above 50% over time while decreasing in the control arm, with a significant difference between arms at 6 months [AOR (95% CI) = 3.5 (1.3, 9.5)]. There were no significant differences between arms in the other outcomes. The MEPS intervention was effective in increasing PrEP uptake and HIV testing in people leaving incarceration. Interventions that implement peer mentor support and incentives to encourage service engagement can improve engagement in HIV prevention services among populations that experience unique barriers to care. This study was registered with ClinicalTrials.gov on July 25, 2019 (NCT04036396). Resumen: El VIH afecta de manera desproporcionada a personas minorizadas, especialmente a aquellas con identidades interseccionales minorizadas. La encarcelación también impacta de manera desproporcionada a estas poblaciones y aumenta el riesgo de VIH, en parte debido a la disrupción que causa en sus vidas, redes sociales y acceso a la atención médica. Desarrollamos MEPS, una intervención de seis meses diseñada para apoyar de manera integral la prevención del VIH en hombres que tienen sexo con hombres y mujeres transgénero que están saliendo de la cárcel. Probamos MEPS mediante un ensayo aleatorizado y controlado 1:1 con 208 participantes. Todos los participantes recibieron una evaluación de necesidades y un plan de bienestar personalizado, seguidos por el cuidado estándar o la intervención MEPS. MEPS integró el apoyo de un Peer Mentor (mentor entre pares), incentivos por participación en servicios sociales y de salud, y una aplicación móvil. Los participantes completaron evaluaciones al inicio y seguimientos a los 3, 6 y 9 meses. Evaluamos los cambios en el uso de PrEP mediante un modelo de trayectoria grupal; y los cambios en pruebas de VIH e ITS, uso frecuente de sustancias y reincidencia mediante modelos logísticos mixtos; así como los cambios en pruebas de hepatitis C y en tener un lugar regular de atención mediante modelos de Poisson. Los participantes del grupo MEPS tuvieron una probabilidad significativamente mayor que los del grupo control de estar entre quienes usaron PrEP [OR ajustado (IC 95%) = 3.8 (1.8, 8.0)]. Las pruebas recientes de VIH en el grupo MEPS se mantuvieron por encima del 50% con el tiempo, mientras que disminuyeron en el grupo control, con una diferencia significativa entre grupos a los 6 meses [OR ajustado (IC 95%) = 3.5 (1.3, 9.5)]. No se observaron diferencias significativas entre grupos en los otros resultados. La intervención MEPS fue eficaz para aumentar el uso de PrEP y las pruebas de VIH en personas que salen de la cárcel. Las intervenciones que implementan el apoyo de mentores pares e incentivos para fomentar la participación en servicios pueden mejorar la vinculación con servicios de prevención del VIH en poblaciones que enfrentan barreras únicas para acceder a la atención. Este estudio fue registrado en ClinicalTrials.gov el 25 de julio de 2019 (NCT04036396). pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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