Relation of volatile organic compounds to renal function in American adolescents: three statistical models.
This study was conducted to evaluate the relationship between 17 urinary metabolites of volatile organic compounds (mVOCs) in adolescents and renal function parameters (estimated glomerular filtration rate (eGFR), albumin-to-creatinine ratio (ACR), urinary albumin, serum uric acid (SUA), and blood u...
| Published in: | International Journal of Environmental Health Research Vol. 35; no. 10; pp. 2759 - 2771 |
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| Main Authors: | , , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Taylor & Francis Ltd
Oct2025
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=189081175&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 189081175 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09603123 57L jtl: International Journal of Environmental Health Research issn: 09603123 maglogo: Y pubinfo: dt: Oct2025 vid: 35 iid: 10 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 189081175 182559790 189081175 189081175 10.1080/09603123.2025.2461106 189081175 ppf: 2759 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Relation of volatile organic compounds to renal function in American adolescents: three statistical models. aug: au: Zhang, Jiaqi Li, Runhong Wang, Kaiyuan Xu, Tong He, Yue Han, Tianyang Lin, Xinli Jin, Lina affil: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China sug: subj: Organic Chemicals Analysis Metabolites In Adolescence Kidney Function Tests Glomerular Filtration Rate Models, Statistical Albumins Urine Creatinine Urine Uric Acid Blood Blood Urea Nitrogen Human Funding Source China Male Female Adolescence United States Analytic Research Surveys Descriptive Statistics Data Analysis Software Confidence Intervals Regression Biological Markers Urine Adolescent: 13-18 years Male Female ab: This study was conducted to evaluate the relationship between 17 urinary metabolites of volatile organic compounds (mVOCs) in adolescents and renal function parameters (estimated glomerular filtration rate (eGFR), albumin-to-creatinine ratio (ACR), urinary albumin, serum uric acid (SUA), and blood urea nitrogen (BUN)). In adjusted generalised linear models (GLM), mVOCs were positively correlated with eGFR, urinary albumin, and BUN, and mVOCs were negatively correlated with ACR and SUA. Weighted Quartile Sum (WQS) index correlated with eGFR [β(95%CI): 0.040 (0.028, 0.052)], urine albumin [β(95%CI): 0.275 (0.203, 0.622)], SUA [β(95%CI): 0.040 (0.025, 0.055)] and BUN [β(95%CI): 0.102 (0.082, 0.122)]. In Bayesian Kernel Machine Regression (BKMR) model, total compound effect was positively correlated with eGFR, positive associations were observed in high concentration of the mixture with urine albumin and ACR. Findings suggest that single and mixed exposures to mVOCs may affect renal parameters in adolescents. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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