The occurrence, concentration, and human health risk assessment of deoxynivalenol in beer: a global systematic review and meta-analysis.
This study examined the concentration and occurrence of deoxynivalenol (DON) in beer and calculated the health risk to consumers using the target hazard quotient (THQ). The analysis considered the country and type of DON subgroups. Searches were performed in databases including Scopus, Web of Scienc...
| Published in: | International Journal of Environmental Health Research Vol. 35; no. 11; pp. 3622 - 3635 |
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| Main Authors: | , , , , , , |
| Format: | equations & formulas research systematic review tables/charts Journal Article |
| Published: |
Taylor & Francis Ltd
Nov2025
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=189081354&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 189081354 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09603123 57L jtl: International Journal of Environmental Health Research issn: 09603123 maglogo: Y pubinfo: dt: Nov2025 vid: 35 iid: 11 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 189081354 183938430 189081354 189081354 10.1080/09603123.2025.2482073 189081354 ppf: 3622 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The occurrence, concentration, and human health risk assessment of deoxynivalenol in beer: a global systematic review and meta-analysis. aug: au: Nikolenko, Denis A. Fakhri, Yadolah Mehri, Fereshteh Mahmoudizeh, Amirhossein Dehghani, Somayeh Khodadoust, Behnam Mousavi Khaneghah, Amin affil: I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia sug: subj: Risk Assessment Mycotoxins Poisoning Alcoholic Beverages Food Contamination Geographic Factors Human Systematic Review Meta Analysis Embase PubMed Consumer Health Information Czech Republic Switzerland Russia Cameroon Nigeria Kenya Brazil Latvia ab: This study examined the concentration and occurrence of deoxynivalenol (DON) in beer and calculated the health risk to consumers using the target hazard quotient (THQ). The analysis considered the country and type of DON subgroups. Searches were performed in databases including Scopus, Web of Science, Embase, and PubMed from 1 January 2000, to 20 February 2024. Our study included 26 papers with 154 data reports. The rank order of DON types based on occurrence was DON (67.38%) > DON-3-Glc (61.45%) > DON-15-Ac (3.43%) > DON-3-Ac (2.58%). Based on concentration, DON (14.658 µg L⁻¹) > DON-3-Glc (14.190 µg L-1) > DON-15-Ac (13.023 µg L⁻¹) > DON-3-Ac (7.550 µg L⁻¹). The highest concentrations of DON, DON-3-Ac, DON-15-Ac, and DON-3-Glc in beer were observed in Cameroon (227.797 µg L⁻¹), Nigeria (27.000 µg L⁻¹), Nigeria (30.000 µg L⁻¹), and the Czech Republic (44.050 µg L⁻¹), respectively. The meta-regression reveals a significant decrease in the occurrence of DON in beer over time (C: −0.014; p-value = 0.016). Despite the higher health risk in Cameroon, Brazil, and Latvia compared to other countries, the health risk assessment revealed no significant non-carcinogenic risk for consumers. pubtype: Academic Journal doctype: equations & formulas meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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