Enhancing Dementia Classification for Diverse Demographic Groups: Using Vision Transformer-Based Continuous Scoring of Clock Drawing Tests.

Objectives Alzheimer's disease and related dementias significantly affect older adults' quality of life. The clock-drawing test (CDT) is a widely used dementia screening tool due to its ease of administration and effectiveness. However, manual CDT-coding in large-scale studies can be time-intensive...

Descripción completa

Detalles Bibliográficos
Publicado en:Journals of Gerontology Series B: Psychological Sciences & Social Sciences Vol. 80; no. 7; pp. 1 - 8
Autores principales: Hu, Mengyao, Murphey, Yi Lu, Qin, Tian, Melipillán, Edmundo R, Zahodne, Laura B, Gonzalez, Richard, Freedman, Vicki A
Formato: Artículo
Publicado: Oxford University Press / USA Jul2025
Materias:
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=189082038&site=ehost-live
header:
  @attributes:
    shortDbName: ssf
    uiTerm: 189082038
    longDbName: Social Sciences Full Text (H.W. Wilson)
    uiTag: AN
  controlInfo:
    bkinfo:
    jinfo:
      jid:
        10795014
        JGB
      jtl: Journals of Gerontology Series B: Psychological Sciences & Social Sciences
      issn: 10795014
      maglogo: N
    pubinfo:
      dt: Jul2025
      vid: 80
      iid: 7
      pid: 622
      pub: Oxford University Press / USA
    artinfo:
      ui:
        189082038
        10.1093/geronb/gbaf065
      ppf: 1
      ppct: 7
      formats:
      tig:
        atl: Enhancing Dementia Classification for Diverse Demographic Groups: Using Vision Transformer-Based Continuous Scoring of Clock Drawing Tests.
      aug:
        au:
          Hu, Mengyao
          Murphey, Yi Lu
          Qin, Tian
          Melipillán, Edmundo R
          Zahodne, Laura B
          Gonzalez, Richard
          Freedman, Vicki A
        affil:
          Management, Policy, and Community Health, School of Public Health, the University of Texas Health Science Center at Houston, Houston, Texas, USA
          Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA
          College of Engineering and Computer Science, University of Michigan–Dearborn, Dearborn, Michigan, USA
          Department of Psychology, University of Michigan, Ann Arbor, Michigan, USA
      su:
        United States
        Health services accessibility
        African Americans
        Psychometrics
        Health equity
        Educational attainment
        Alzheimer's disease diagnosis
        Cognition disorders diagnosis
        Predictive tests
        Alzheimer's disease
        Receiver operating characteristic curves
        Statistical significance
        Research funding
        Research evaluation
        Descriptive statistics
        Routine diagnostic tests
        Deep learning
        Artificial neural networks
        Neuropsychological tests
        Research methodology
        Data analysis software
        Algorithms
        Sensitivity & specificity (Statistics)
      sug:
        subj:
          Health services accessibility
          African Americans
          Psychometrics
          Health equity
          Educational attainment
          United States
          Alzheimer's disease diagnosis
          Cognition disorders diagnosis
          Predictive tests
          Alzheimer's disease
          Receiver operating characteristic curves
          Statistical significance
          Research funding
          Research evaluation
          Descriptive statistics
          Routine diagnostic tests
          Deep learning
          Artificial neural networks
          Neuropsychological tests
          Research methodology
          Data analysis software
          Algorithms
          Sensitivity & specificity (Statistics)
      keyword:
        Cognitive function
        Deep learning neural networks
        Machine learning
        Cognitive function
        Deep learning neural networks
        Machine learning
      ab: Objectives Alzheimer's disease and related dementias significantly affect older adults' quality of life. The clock-drawing test (CDT) is a widely used dementia screening tool due to its ease of administration and effectiveness. However, manual CDT-coding in large-scale studies can be time-intensive and prone to coding errors and is typically limited to ordinal responses. In this study, we developed a continuous CDT score using a deep learning neural network (DLNN) and evaluated its ability to classify participants as having dementia or not. Methods Using a nationally representative sample of older adults from the National Health and Aging Trends Study (NHATS), we trained deep learning models on CDT images to generate both ordinal and continuous scores. Using a modified NHATS dementia classification algorithm as a benchmark, we computed the area under the receiver operating characteristic curve for each scoring approach. Thresholds were determined by balancing sensitivity and specificity, and demographic-specific thresholds were compared to a uniform threshold for classification accuracy. Results Continuous CDT scores provided more granular thresholds than ordinal scores for dementia classification, which vary by demographic characteristics. Lower thresholds were identified for Black individuals, those with lower education, and those ages 90 or older. Compared to ordinal scores, continuous scores also allowed for a more balanced sensitivity and specificity. Discussion This study demonstrates the potential of continuous CDT generated by DLNN to enhance dementia classification. By identifying demographic-specific thresholds, it offers a more inclusive and adaptive approach, which could lead to improved guidelines for using CDT in dementia screening.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
    refInfo:
    copyright:
      @attributes:
        flag: N
    holdings:
      @attributes:
        islocal: N