Effectiveness of rapid urease, serum antibody, and histopathological detection of helicobacter pylori infection in children.
This was an original study, aimed to explore the efficacy of rapid urease, serum antibody and histopathological detection of Helicobacter pylori (Hp) infection in children. One hundred and forty (140)children admitted to Liaoning Cancer Hospital & Institute due to gastrointestinal symptoms who under...
| Publicado en: | African Journal of Reproductive Health Vol. 29; no. 10; pp. 100 - 109 |
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| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Women's Health & Action Research Centre
Oct2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=189102237&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 189102237 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11184841 G7W jtl: African Journal of Reproductive Health issn: 11184841 maglogo: N pubinfo: dt: Oct2025 vid: 29 iid: 10 pid: 12182 pub: Women's Health & Action Research Centre place: Benin City Edostate 234, <Blank> artinfo: ui: 189102237 189102237 189102237 10.29063/ajrh2025/v29i10.10 189102237 ppf: 100 ppct: 9 formats: tig: atl: Effectiveness of rapid urease, serum antibody, and histopathological detection of helicobacter pylori infection in children. aug: au: Yang, Dan Mo, Taoran Chen, Qian Liang, Lei affil: Department of Clinical Laboratory, Liaoning Cancer Hospital & Institute, Shenyang, Liaoning 110034, China sug: subj: Urease Analysis Antibodies Blood Histological Techniques Evaluation Helicobacter Infections Diagnosis Helicobacter Infections Diagnosis Pediatric Care Human China Male Female Child Adolescence Nonexperimental Studies Cancer Care Facilities Descriptive Statistics Comparative Studies Sensitivity and Specificity Data Analysis Software T-Tests Chi Square Test Validity Gastroscopy Biopsy Histocytochemistry Child: 6-12 years Adolescent: 13-18 years Male Female ab: This was an original study, aimed to explore the efficacy of rapid urease, serum antibody and histopathological detection of Helicobacter pylori (Hp) infection in children. One hundred and forty (140)children admitted to Liaoning Cancer Hospital & Institute due to gastrointestinal symptoms who underwent electronic gastroscopy from June 2020 to June 2022 were included. Among the 140 children, 72 were positive for Hp infection by rapid urease, 71 with serum antibody, and 67 with histopathology. The specificities of Hp infection detected by the three methods -- rapid urease, serum antibody and histology were 88.7%, 90.6% and 91.7%, respectively. We conclude that the combination of three detection methods of rapid urease, serum antibody and histopathology can improve the sensitivity, specificity, and the accuracy of Hp detection. Il s'agit d'une étude originale visant à évaluer l'efficacité de l'uréase rapide, des anticorps sériques et de la détection histopathologique de l'infection à Helicobacter pylori (Hp) chez l'enfant. Cent quarante (140) enfants admis Liaoning Cancer Hospital & Institute pour symptômes gastro-intestinaux et ayant subi une gastroscopie électronique entre juin 2020 et juin 2022 ont été inclus. Parmi ces 140 enfants, 72 étaient positifs pour l'infection à Hp par l'uréase rapide, 71 par les anticorps sériques et 67 par l'histopathologie. Les spécificités de l'infection à Hp détectée par les trois méthodes -- uréase rapide, anticorps sériques et histologie -- étaient respectivement de 88,7 %, 90,6 % et 91,7 %. Nous concluons que la combinaison de ces trois méthodes de détection -- uréase rapide, anticorps sériques et histopathologie -- peut améliorer la sensibilité, la spécificité et la précision de la détection de Hp. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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