Effect modification in therapeutic impact of nalmefene on alcohol dependence by ADH1B polymorphism: A secondary analysis of a Japanese randomized clinical trial.
Background and Aims: The association between alcohol‐metabolizing enzyme polymorphisms and treatment response to nalmefene for alcohol dependence has not been studied. We aimed to determine whether alcohol‐metabolizing enzyme polymorphisms, specifically ADH1B rs1229984 and ALDH2 rs671, modify the tr...
| Publicado en: | Addiction Vol. 120; no. 12; pp. 2423 - 2435 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Wiley-Blackwell
Dec2025
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| Acceso en línea: | Ver este registro en EBSCOhost |