Externalizing as a common genetic influence for a broad spectrum of substance use and behavioral conditions: A developmental perspective from the Avon Longitudinal Study of Parents and Children.

Background and aims: Recent large studies have established the genetic basis of several conceptually linked phenotypes of externalizing. Polygenic risk scores (PRSs) for these constructs are associated with a range of substance use and mental disorder phenotypes but have not been examined with both...

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Bibliographic Details
Published in:Addiction Vol. 120; no. 12; pp. 2559 - 2573
Main Authors: Deng, Wei Q., Belisario, Kyla, Doggett, Amanda, Pigeyre, Marie, Pare, Guillaume, Munafò, Marcus R., MacKillop, James
Format: research tables/charts Journal Article
Published: Wiley-Blackwell Dec2025
Online Access:View this record in EBSCOhost