PSMA radioligand uptake correlates with PSMA expression in high-grade glioma and brain metastasis: insights from a prospective PET-MRI guided multiregional biopsy study.

Purpose: Prostate-specific membrane antigen (PSMA) is a potential target for radioligand therapy (RLT) in neuro-oncology. This study investigates the direct relation between [68Ga]Ga-PSMA-11 uptake on PET and PSMA expression in the tumour micro-environment of high-grade glioma (HGG) and brain metast...

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Bibliographic Details

Published in:	European Journal of Nuclear Medicine & Molecular Imaging Vol. 52; no. 13; pp. 4870 - 4882
Main Authors:	Pruis, Ilanah J., van Dis, Vera, Maas, Sybren L. N., Balvers, Rutger K., van den Bosch, Thierry P. P., Segbers, Marcel, Veldhuijzen van Zanten, Sophie E. M.
Format:	Journal Article
Published:	Springer Nature Nov2025
Online Access:	View this record in EBSCOhost