Chemical exchange saturation transfer magnetic resonance imaging of the kidney: applications and challenges.

The kidney plays a crucial role in regulating the acid-base balance of the body. The development of kidney diseases is often accompanied by changes in the renal PH, protein, glucose, urea, and other metabolites. Chemical exchange saturation transfer (CEST) imaging is a new magnetic resonance imaging...

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Publicado en:Abdominal Radiology Vol. 50; no. 12; pp. 5934 - 5948
Autores principales: Liu, Lu, Guo, Songlin, Xing, Zhaoyu, Yu, Xingtian, Mi, Wenxia, Ding, Jiule, Chen, Jie, Xing, Wei, Pan, Liang
Formato: Journal Article
Publicado: Springer Nature Dec2025
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Chemical exchange saturation transfer magnetic resonance imaging of the kidney: applications and challenges.
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          Liu, Lu
          Guo, Songlin
          Xing, Zhaoyu
          Yu, Xingtian
          Mi, Wenxia
          Ding, Jiule
          Chen, Jie
          Xing, Wei
          Pan, Liang
        affil: https://ror.org/05a9skj35 Department of Radiology, Third Affiliated Hospital of Soochow University, Changzhou, China
      sug:
      ab: The kidney plays a crucial role in regulating the acid-base balance of the body. The development of kidney diseases is often accompanied by changes in the renal PH, protein, glucose, urea, and other metabolites. Chemical exchange saturation transfer (CEST) imaging is a new magnetic resonance imaging (MRI) technique based on the chemical exchange between solute and water protons. The potential of CEST imaging in renal metabolic imaging stems from its ability to provide image contrast based on specific molecular compositions at relevant millimolar physiological concentrations. In this article, we briefly introduce the fundamental principles of CEST imaging and its applications in various renal disorders, including acute kidney injury, chronic kidney disease, renal tumors, and renal allograft rejection. Finally, we discuss the challenges and prospects of CEST imaging in the field of kidney diseases.
      pubtype: Academic Journal
      doctype: Journal Article
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    language: English
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