Direct aspiration versus stent retriever as First-line thrombectomy techniques for acute Basilar artery occlusions: an updated systematic review and Meta-Analysis.
Background: Endovascular thrombectomy is the primary treatment for acute basilar artery occlusion (BAO), with direct aspiration (DA) and stent retriever (SR) as the main techniques. This updated meta-analysis aims to compare these two techniques in terms of efficacy and safety outcomes. Methods: A s...
| Publicado en: | Neuroradiology Vol. 67; no. 10; pp. 2851 - 2868 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=189357981&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 189357981 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00283940 NYZ jtl: Neuroradiology issn: 00283940 maglogo: N pubinfo: dt: Oct2025 vid: 67 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 189357981 187592946 189357981 189357981 10.1007/s00234-025-03749-0 189357981 ppf: 2851 ppct: 17 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Direct aspiration versus stent retriever as First-line thrombectomy techniques for acute Basilar artery occlusions: an updated systematic review and Meta-Analysis. aug: au: Lee, Wei Jun Correia Maciel, Rafaela Abo Kasem, Rahim Najdawi, Zaid Elfil, Mohamed Khasawneh, Mohammad Leite, Marianna Barbosa Pereira da Silva, Davi dos Reis Schevz, Rodrigo Quaresma Sardella, Gabriela Toth, Gabor Al-Mufti, Fawaz affil: https://ror.org/0041qmd21 SUNY Downstate Medical Center, Brooklyn, United States sug: subj: Basilar Artery Pathology Arterial Occlusive Diseases Surgery Aspiration Stents Thrombectomy Methods Patient Safety Treatment Outcomes Human Systematic Review Meta Analysis PubMed Embase Cochrane Library Intracranial Hemorrhage Confidence Intervals Odds Ratio Descriptive Statistics Probability Hypertension Diabetes Mellitus Hyperlipidemia ab: Background: Endovascular thrombectomy is the primary treatment for acute basilar artery occlusion (BAO), with direct aspiration (DA) and stent retriever (SR) as the main techniques. This updated meta-analysis aims to compare these two techniques in terms of efficacy and safety outcomes. Methods: A search was performed across PubMed, Embase, and Cochrane databases on December 23, 2024. Primary outcomes included good and favorable functional outcomes. Secondary outcomes included procedural outcomes, such as successful and complete recanalization, and safety outcomes, including symptomatic intracranial hemorrhage and mortality at 90 days. Leave-one-out sensitivity analysis was used to assess each study's influence on the pooled effect by systematically excluding one study at each time. Results: Out of 4,424 studies initially screened, a total of 14 studies with 1,851 patients were ultimately included (DA = 830, SR = 1,021). There were no significant differences in favorable and good functional outcomes (OR 1.07; 95% CI 0.82–1.39; P = 0.626; OR 1.19; 95% CI 0.94–1.50; P = 0.152, respectively) nor mortality (OR 0.83; 95% CI 0.63–1.09; P = 0.177). A significant difference was observed in complete recanalization rates in sensitivity analyses, favoring DA, which was not evident in the successful recanalization rates. The DA group also demonstrated a lower risk of sICH (OR 0.56; 95% CI 0.34–0.93; P = 0.025). Conclusion: Our meta-analysis shows that DA and SR techniques for BAO thrombectomy each have distinct procedural trade-offs. Due to data heterogeneity and observational design, neither method can be definitively recommended. Treatment decisions should be individualized until high-quality randomized data are available. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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