Neurofibromatosis Type 1 and the Search for Effective Tumor Therapies Using High-Throughput Drug Screening.

Simple Summary: In this review, we examine five decades of drug screening efforts aimed at developing treatments for Neurofibromatosis Type 1 (NF1). We begin with an overview of the clinical manifestations of NF1, followed by a discussion of early attempts to target the RAS pathway before the advent...

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Publicado en:Current Oncology Vol. 32; no. 11; pp. 649 - 699
Autores principales: Bouley, Stephanie J., Housden, Benjamin E., Walker, James A.
Formato: Journal Article
Publicado: MDPI Nov2025
Acceso en línea:Ver este registro en EBSCOhost