Rapid and specific immunoPET imaging of Nectin-4 in gastric cancer and non-small cell lung cancer using [64Cu]Cu-NOTA-EV-F(ab')2.

Purpose: This study aimed to develop and evaluate [64Cu]Cu-NOTA-EV-F(ab')2 as a rapid and specific immunoPET imaging probe targeting Nectin-4 in gastric cancer (GC) and non-small cell lung cancer (NSCLC). Materials and methods: F(ab')2 fragments were generated from enfortumab vedotin (EV) using IdeS...

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Bibliographic Details

Published in:	European Journal of Nuclear Medicine & Molecular Imaging Vol. 53; no. 1; pp. 619 - 633
Main Authors:	Huang, Wenpeng, Sun, Xinyao, Li, Xiaoyan, Hsu, Jessica C., Qiu, Yongkang, DeLuca, Molly C., Engle, Jonathan W., Li, Liming, Lu, Jun, Wang, Tianyao, Kang, Lei, Cai, Weibo
Format:	Journal Article
Published:	Springer Nature Dec2025
Online Access:	View this record in EBSCOhost