[68Ga]Ga-interleukin-2 for imaging activated T-lymphocytes: biochemical characterization and phase I study in normal subjects.

Purpose: This study aimed to develop a ready-to-use kit for 68Ga-labelling of interleukin-2 (IL2) facilitating PET imaging of activated T-lymphocytes. Methods: Human recombinant IL2 (hrIL2) and Aldesleukin (desIL2), conjugated with two different chelators (NODAGA and THP) were compared. Conjugated-I...

Descripción completa

Detalles Bibliográficos

Publicado en:	European Journal of Nuclear Medicine & Molecular Imaging Vol. 53; no. 1; pp. 544 - 557
Autores principales:	Signore, Alberto, Galli, Filippo, Varani, Michela, Campagna, Giuseppe, Bentivoglio, Valeria, Accardo, Antonella, Morelli, Giancarlo, Lauri, Chiara
Formato:	Journal Article
Publicado:	Springer Nature Dec2025
Acceso en línea:	Ver este registro en EBSCOhost