Lysosome-escaping and nucleus-targeting nanomedicine for enhanced cancer catalytic internal radiotherapy.
Purpose: Radio-nanomedicine, such as 125I-labelled TiO2 nanoparticles (125I-TiO2 NPs), presents a promising tumour treatment approach. By leveraging 125I as an electron donor to activate TiO2 NPs and promote γ-ray–induced H2O radiolysis, 125I-TiO2 generates reactive oxygen species (ROS) and induces...
| Publicado en: | European Journal of Nuclear Medicine & Molecular Imaging Vol. 53; no. 1; pp. 574 - 589 |
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| Autores principales: | , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Dec2025
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| Acceso en línea: | Ver este registro en EBSCOhost |